Consolidated Statements of Operations (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Income Statement [Abstract]
Licensing revenue	$ 27,600	$ 5,119	$ 302,059
Other revenue			145,152
Total revenues	27,600	5,119	447,211
Operating Expenses:
Research and development	11,298,931	8,670,710	3,796,127
Selling, general and administrative	8,365,137	6,374,429	4,905,757
Total operating expenses	19,664,068	15,045,139	8,701,884
Loss from operations	(19,636,468)	(15,040,020)	(8,254,673)
Other Income (Expense):
Interest income	3,052	5,466	4,808
Interest expense	(3,899,967)	(504,858)	(13,926)
Debt financing costs		(455,000)
Loss on extinguishment of debt/payables			(1,514)
Loss on disposals of assets		(21,272)	(1,348)
Gain (loss) on revaluation of derivative warrant liability	4,465,986	3,683,676	(1,762,938)
Other income (expense), net	569,071	2,708,012	(1,774,918)
Net loss	(19,067,397)	(12,332,008)	(10,029,591)
Deemed dividend on beneficial conversion feature convertible preferred stock	(371,140)		(1,975,211)
Deemed dividend on repricing of warrants			(4,559,761)
Accretion of dividends on Series B Convertible Perpetual Redeemable Preferred Stock			(157,733)
Net loss applicable to common shareholders	$ (19,438,537)	$ (12,332,008)	$ (16,722,296)
Net loss per common share, basic and diluted	$ (2.33)	$ (3.12)	$ (4.89)
Basic and diluted weighted average common shares outstanding	8,359,837	3,955,046	3,417,490