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Consolidated Balance Sheets (USD $)
Dec. 31, 2013
Dec. 31, 2012
Current Assets:    
Cash and cash equivalents $ 8,055,385 $ 3,747,210
Cash restricted pursuant to letters of credit 302,488 407,463
Current portion of deferred financing costs 968,004 968,004
Prepaid expenses and other current assets 49,221 75,626
Total current assets 9,375,098 5,198,303
Property and Equipment, at cost:    
Computer equipment 323,488 367,854
Office and laboratory equipment (including assets under capitalized leases) 728,152 732,296
Furniture and fixtures 755,444 728,269
Manufacturing equipment 111,980 156,435
Leasehold improvements 825,589 818,939
Property and equipment, at cost 2,744,653 2,803,793
Less-Accumulated depreciation and amortization (1,248,846) (1,165,398)
Net property and equipment (including assets under capitalized leases) 1,495,807 1,638,395
Other Assets:    
Restricted cash 10,490 9,740
Intangible assets, net of accumulated amortization 9,625,000 9,625,000
Deferred financing costs 2,581,324 3,549,328
Other assets 1,576 826
Total other assets 12,218,390 13,184,894
Total assets 23,089,295 20,021,592
Current Liabilities:    
Accounts payable 1,036,320 2,319,219
Deferred revenue from licensing arrangements, current portion 76,428 90,228
Current portion of capital lease obligation 1,361 2,527
Derivative warrant liability 1,119,155 5,585,141
Accrued expenses and other current liabilities 1,411,107 1,581,448
Total current liabilities 3,644,371 9,578,563
Capital lease obligation, net of current portion    1,361
Note payable, net of discount    120,834
Deferred revenue from licensing arrangements, net of current portion 76,428 90,228
Total liabilities 3,720,799 9,790,986
Convertible Preferred Stock:    
Series C, $0.01 par value, authorized 10,000 shares, issued and outstanding 1,000 and 9,974.185 shares at December 31, 2013 and 2012, respectively 10 100
Series D, $0.01 par value, authorized 3,600,000 shares, issued and outstanding 1,000,000 and 3,006,000 shares at December 31, 2013 and 2012, respectively (preference in liquidation of $1,000,000 and $3,006,000) 10,000 30,060
Series E, $0.01 par value, authorized 1,748,613 shares, issued and outstanding 1,748,613 shares at December 31, 2013 17,486   
Common stock, $0.01 par value, authorized 150,000,000 shares, issued and outstanding 11,776,578 and 4,437,346 shares at December 31, 2013 and 2012, respectively 117,764 44,374
Additional paid-in capital 132,192,648 104,058,087
Accumulated deficit (112,969,412) (93,902,015)
Total stockholders' equity 19,368,496 10,230,606
Total liabilities and stockholders' equity $ 23,089,295 $ 20,021,592