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Consolidated Statements of Changes in Stockholders' Equity (USD $)
Preferred Stock
Common Stock
Additional Paid-in Capital
Common Stock Subscribed
Accumulated Deficit
Total
Beginning balance, Amount at Dec. 31, 2009 $ 51 $ 270,459 $ 74,155,716    $ (67,393,620) $ 7,032,606
Beginning balance, Shares at Dec. 31, 2009 5,059 27,045,792        
Exercise of warrants, Shares   35,714        
Exercise of warrants, Amount   357 (357)         
Share-based payments - restricted stock, net of forfeitures, Shares   363,000        
Share-based payments - restricted stock, net of forfeitures, Amount   3,630 389,619       393,249
Share-based payments - options, net of forfeitures       164,810       164,810
Fair value of warrants issued for services     616,634     616,634
Fair value of options issued for services     59,471     59,471
Common Stock issued to charitable organization, Shares   60,000        
Common Stock issued to charitable organization , Amount   600 112,800       113,400
Issuance of Common Stock, net of cash issuance costs of $188,333 and non-cash costs of $468,741, Shares   3,356,739        
Issuance of Common Stock, net of cash issuance costs of $188,333 and non-cash costs of $468,741, Amount   33,568 3,484,485       3,518,053
Fair value of fully vested Common Stock issued for services, Shares   265,000        
Fair value of fully vested Common Stock issued for services, Amount   2,650 462,850       465,500
Fair value of derivative warrant liabilities reclassified to additional paid-in capital       200,357       200,357
Dividends on Series B Preferred Stock, Shares 13          
Dividends on Series B Preferred Stock, Amount                  
Common Stock subscription, 285,000 shares       285,000   285,000
Net Loss         (4,146,796) (4,146,796)
Ending balance, Amount at Dec. 31, 2010 51 311,264 79,646,385 285,000 (71,540,416) 8,702,284
Ending balance, Shares at Dec. 31, 2010 5,072 31,126,245        
Exercise of warrants, Shares 3,225 2,303,456        
Exercise of warrants, Amount 32 23,035 4,896,278       4,919,345
Series B Preferred Stock redeemed for Series C Preferred Stock in warrant exercise, Shares 1,661          
Series B Preferred Stock redeemed for Series C Preferred Stock in warrant exercise, Amount 17   (17)      
Share-based payments - restricted stock, net of forfeitures, Shares   190,000        
Share-based payments - restricted stock, net of forfeitures, Amount   1,900 (1,900)         
Share-based payments - options, net of forfeitures       836,866       836,866
Fair value of fully vested Common Stock issued for services, Shares   138,000        
Fair value of fully vested Common Stock issued for services, Amount   1,380 447,560       448,940
Fair value of derivative warrant liabilities reclassified to additional paid-in capital       2,272,597       2,272,597
Common Stock subscription, 285,000 shares       6,667   6,667
Issuance of Common Stock and warrants, net of cash issuance costs of $109,636 and non-cash costs of $41,363, Shares   3,550,449        
Issuance of Common Stock and warrants, net of cash issuance costs of $109,636 and non-cash costs of $41,363, Amount   35,505 6,403,984 (285,000)    6,154,489
Issuance of Series D Preferred Stock and warrants, net of cash issuance costs of $21,299, Shares 3,506,000          
Issuance of Series D Preferred Stock and warrants, net of cash issuance costs of $21,299, Amount 35,060    3,449,642       3,484,702
Series B Preferred Stock dividend paid-in-kind, Shares 16          
Series B Preferred Stock dividend paid-in-kind, Amount                  
Common Stock issued in Series D Preferred Stock conversion, Shares (500,000) 500,000        
Common Stock issued in Series D Preferred Stock conversion, Amount (5,000) 5,000            
Common Stock and warrants issued to settle short-term note, Shares   30,000        
Common Stock and warrants issued to settle short-term note, Amount   300 35,200       35,500
Exercise of stock options, Shares   705,844        
Exercise of stock options, Amount   7,058 129,732       136,790
Net Loss         (10,029,591) (10,029,591)
Ending balance, Amount at Dec. 31, 2011 $ 30,160 $ 385,442 $ 98,116,327 $ 6,667 $ (81,570,007) $ 16,968,589
Ending balance, Shares at Dec. 31, 2011 3,015,974 38,543,994