EXHIBIT 11

CURAGEN CORPORATION
COMPUTATION OF NET LOSS PER SHARE
(unaudited)

               
       
Three Months Ended
       
March 31,
       
 
       
2000
 
1999
 
       
 
 
Net loss      
($5,039,496)
 
($7,206,927)
 


 
Basic and diluted net loss per share (1)      
$ (0.14)
 
$(0.27)
 
       

 
Weighted average number of shares used in computing      
 
 
basic and diluted net loss per share (1)      
36,058,153
 
26,804,842
 
       

 
               

(1) The effects of the two-for-one stock split have been reflected in the calculations of basic and diluted net loss per share for all periods presented.