Collaborative Research, Development and License Agreements - Additional Information (Detail) - USD ($) $ in Thousands		1 Months Ended				3 Months Ended	12 Months Ended
	Dec. 31, 2022	Oct. 31, 2022	Aug. 31, 2022	Sep. 30, 2021	May 31, 2021	Dec. 31, 2020	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Oct. 31, 2021	Jan. 31, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							$ 722,683	$ 439,442	$ 46,551
Inventory write-offs recognized							34,300	0
Accrued liabilities	$ 30,719						30,719	49,796
Other receivables	2,385						2,385	15,600
Inventory write-off							34,288	2,588	0
CpG 1018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							288,000	72,200
Inventory write-offs recognized							34,300
Final payment for remaining quantities	29,300
Modified Purchase Order
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							53,200
Coalition for Epidemic Preparedness Innovations
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Interest- free unsecured forgivable loan											$ 99,000
Advance payment from customer	175,000						175,000
Accrued liabilities	107,700						107,700	128,800
Long-term deferred revenue	0						0	5,400
Other receivables	0						0	14,600
Clover
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Advance payment received			$ 68,000
Cancellation fees			24,100
Clover | CpG 1018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential future collection receivable		$ 10,000
Clover | Modified Purchase Order | CpG 1018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Final payment for remaining quantities			$ 14,600
Valneva SE
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue	55,400						55,400
Advance payment from customer										$ 55,400
Consideration Allocated To The Remaining Performance Obligation										$ 55,400
U.S. Department of Defense
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							8,800	500
Proceeds from grant				$ 22,000
Reservation Agreement | Coalition for Epidemic Preparedness Innovations
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized						$ 6,300
Reservation fees									6,300
Reservation Agreement | Coalition for Epidemic Preparedness Innovations Partners
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Increase in interest free unsecured forgiveable loan maximum borrowing capacity					$ 77,400
Interest free unsecured forgiveable loan Maximum borrowing capacity					$ 176,400
Supply Agreement | Clover
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contract asset balance	71,300						71,300	62,500
Accounts receivable	0						0	2,100
Supply Agreement | Biological E. Limited
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized		$ 60,200					206,200	185,700
Accounts receivable	117,800						117,800	96,100
Supply Agreement | PT Bio Farma (Persero)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							25,400
Deferred revenue	0						0
Accounts receivable	0						0
Supply Agreement | Medigen
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized								26,700	1,200
Accounts receivable	0						0	2,400
Supply Agreement | Valneva SE
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							68,000	89,400	$ 2,000
Deferred revenue	0						0	55,400
Accounts receivable	$ 0						0	$ 0
Clover Amendment No 2
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized							$ 87,000