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Note 9 - Stockholders' Deficit - Common Stock Reserved for Future Issuance (Details) - shares
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Stock options outstanding (in shares) 1,032,211    
Shares available for grant under equity incentive plan (in shares) 732,149 1,060,400 1,114,400
Estimated common shares issuable upon conversion of notes payable and accrued interest (in shares) 383,947    
Class of Warrant or Right, Outstanding 2,035,197    
(in shares) 4,183,504