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Note 9 - Stockholders' Equity (Deficit) (Tables)
12 Months Ended
Dec. 31, 2018
Notes Tables  
Schedule of Common Stock Reserved for Future Issuance [Table Text Block]
Stock options outstanding
   
1,032,211
 
Shares available for grant under equity incentive plan
   
732,149
 
Estimated common shares issuable upon conversion of notes payable and accrued interest
   
383,947
 
Common shares issuable under outstanding commons stock purchase warrants
   
2,035,197
 
     
4,183,504