EXHIBIT 99.1

FOR IMMEDIATE RELEASE	CONTACT:
	Colleen McCormick, Investor Relations
	617-779-7892
	cmccormick@amicas.com

AMICAS REPORTS FINANCIAL RESULTS FOR THE THIRD QUARTER
ENDED SEPTEMBER 30, 2008
Positive cash flow from operations, updated guidance, and new stock repurchase program

Boston, MA, November 3, 2008 /PRNewswire/ — AMICAS, Inc. (NASDAQ: AMCS), a leader in radiology and medical image and information management solutions, today reported unaudited financial results for the third quarter ended September 30, 2008.

Q3 Financial Highlights

Revenue: Total revenues for the third quarter of 2008 were $12.3 million, compared to $13.3 million for the third quarter of 2007.

Operating Loss: Operating loss for the third quarter of 2008 was $1.2 million, compared to an operating loss of $521,000 for the third quarter of 2007.

Net Loss/Income: The Company’s net loss for the third quarter of 2008 was $809,000, or $(0.02) per share, compared to net income of $374,000, or $0.01 per share, for the third quarter of 2007.

In the third quarter of 2008, both operating loss and net loss included $438,000 of non-cash stock-based compensation expense and $835,000 of depreciation and amortization. In the third quarter of 2007, both operating loss and net income included $514,000 of non-cash stock-based compensation expense and $789,000 of depreciation and amortization.

Pro-forma EBITDA: Pro-forma EBITDA, a non-GAAP financial measure, was $87,000 in the third quarter of 2008 as compared to $782,000 in the third quarter of 2007.

Pro-forma EBITDA refers to net income, adjusted for amortization, depreciation, interest, taxes, and stock compensation expense. A reconciliation of net loss/income as determined under GAAP to pro-forma EBITDA is included below. Management believes that its pro-forma EBITDA measurement, when viewed in addition to the Company’s reported GAAP results, provides an additional meaningful measure of operating performance, enabling investors to more thoroughly evaluate current performance in comparison to past performance. This information will necessarily differ from comparable information that may be provided by other companies and should not be considered in isolation or as an alternative to the Company’s operating and other financial information determined under GAAP.

Cash and Cash Flow: AMICAS ended the third quarter of 2008 with a cash, cash equivalents, and marketable securities balance of $54.0 million, no long term debt, and working capital of $47.0 million. For the third quarter ended September 30, 2008, net cash provided by operations was $1.9 million.

Stock Repurchase: The Company repurchased approximately 985,000 shares of its common stock for approximately $2.7 million in the third quarter of 2008.

Fiscal Year-to-Date Financial Highlights

Revenue: Total revenues for the first nine months of 2008 were $38.7 million, compared to $38.2 million for the first nine months of 2007.

Operating Loss: Operating loss for the first nine months of 2008 was $3.0 million, compared to an operating loss of $2.7 million for the first nine months of 2007.

Net Loss/Income: The Company’s net loss for the first nine months of 2008 was $1.4 million, or $(0.03) per share, compared to net income of $40,000, or $0.00 per share, for the first nine months of 2007.

For the first nine months of 2008, both operating loss and net loss included $1.1 million of non-cash stock-based compensation expense and $2.5 million of depreciation and amortization. For the first nine months of 2007, both operating loss and net income included $1.5 million of non-cash stock-based compensation expense, and $2.3 million of depreciation and amortization.

Pro-forma EBITDA: For the first nine months of 2008, pro-forma EBITDA was $552,000 as compared to $1.2 million for the same period in 2007.

Cash Flow: For the first nine months of 2008, net cash provided by operations was $3.2 million as compared to $5.6 million for the same period in 2007.

Stock Repurchase: In the fourth quarter of 2007, the Board of Directors directed the Company to initiate a $25 million stock repurchase plan. The Company repurchased approximately 9.6 million shares for approximately $25 million in total under this program. During 2006, under a previously authorized stock repurchase plan, the Company repurchased 4.5 million shares of its common stock for approximately $15 million. In aggregate, the Company has repurchased a total of 14.1 million shares for approximately $40 million since 2006. Both stock repurchase plans are now complete.

Business Perspective

Dr. Stephen Kahane, president, chief executive officer, and chairman of AMICAS, said, “We had our best third quarter bookings in the past several years. Revenue growth was short of our plan, mainly due to our signing more multi-year customer relationships. We expect this trend to continue and, while we reiterate our previously provided guidance related to bookings, we are communicating our adjusted guidance below.”

Dr. Kahane went on to say, “Once again, we maintained positive cash flow from operations while building our business through significant investments in both innovative research and development programs and important distribution initiatives. The third quarter resulted in several large radiology groups making the decision to use AMICAS products as the basis for their automation infrastructure going forward. Over the past year, AMICAS has been able to sign several very sophisticated and informed radiology groups and imaging service providers. We will continue to work hard to help these new partners succeed and to make sure others follow in their footsteps. Our top flight solutions — which include the latest in teleradiology technology, PACS, RIS, revenue cycle management, business intelligence, and zero client referring physician tools — continue to be viewed as extremely easy to install, deploy, and support. These attributes help reduce the total cost of ownership of AMICAS solutions, which can help result in very impressive returns on investment for our customers. As we have mentioned before, it is noteworthy that, despite obstacles such as DRA and other reimbursement-related pressures such as increasing requirements related to pre-authorizations for studies, these groups made the decision to take their automation support to the next level with industry leading offerings from AMICAS.”

Dr. Kahane continued, “The stock buyback program we initiated in the fourth quarter of 2007 was completed in the third quarter of 2008. AMICAS has repurchased the full $25 million authorized under the program put in place in December of last year. Over the past two years, AMICAS has bought back approximately $40 million of its common stock. AMICAS has no debt and has a very strong recurring revenue base from an excellent group of customer partners.”

Dr. Kahane added, “We remain committed to continuing to build a strong company focused on providing excellent innovative image and information management solutions for radiology practices, hospitals, and other imaging-related businesses in healthcare. To continue to get to know us better, we welcome you to our booth at the upcoming RSNA 2008 conference. More information can be found online at www.amicas.com/rsna.”

Looking Forward

AMICAS continues to expect 2008 bookings growth of 10 to 20 percent. Bookings are defined as contractual commitments from customers for licenses, services, hardware, and maintenance/support.

AMICAS now expects 2008 revenues to be between $50.5 million and $51.5 million and pro-forma EBITDA between $(0.5) million and $0.2 million. This is consistent with a net loss of between $3.5 million and $2.8 million or $(0.09) and $(0.07) per share.

Company Announces Authorization of New Stock Repurchase Plan

AMICAS’ Board of Directors has authorized the repurchase of up to $5 million of the company’s common stock from time to time in open market or through negotiated or block transactions in accordance with applicable SEC guidelines and regulations. Additionally, AMICAS may in the future make repurchases pursuant to trading plans meeting the requirements of Rule 10b5-1 of the Securities Exchange Act of 1934. The timing of repurchases, if any, and the number of shares repurchased will depend upon business and market conditions.

Commenting on the share repurchase authorization, Kevin Burns, chief financial officer of AMICAS, said, “The current disruption in the equity markets provides an attractive environment for opportunistic purchases of our common stock. In addition, we are continuing to identify and review other strategic uses of our cash to invest in the growth of our business.”

Conference Call

AMICAS will host a conference call on Tuesday, November 4, at 8:30 a.m. Eastern Time to discuss the Company’s 2008 third fiscal quarter results. Investors and other interested parties may dial in to the call using the toll free number 1-800-862-9098. (conference ID: 7AMICAS). The conference call will also be available via Webcast at www.amicas.com. Following the conclusion of the call, a replay will be available at 1-800-388-9074 or 1-402-220-1117 until December 3, 2008.

AMICAS, AMICAS PACS, AMICAS RIS, AMICAS Financials, AMICAS Documents, AMICAS Dashboards, AMICAS Watch, AMICAS Reach, AMICAS RadStream, RealTime Worklist, Halo Viewer, and Cashfinder Worklist are trademarks, service marks or registered trademarks and service marks of AMICAS, Inc. All other trademarks and company names mentioned are the property of their respective owners.

About AMICAS, Inc.

AMICAS, Inc. (www.amicas.com) is a leader in radiology and medical image and information management solutions. The AMICAS One Suite™ of products provides a complete, end-to-end solution for imaging centers, ambulatory care facilities, and radiology practices. Acute care and hospital clients are provided with a fully integrated, hospital information system-independent PACS that features advanced enterprise workflow support and scalable design. Complementing the AMICAS solution suite is AMICAS Professional Services™, a set of client-centered professional and consulting services that assist our customers with a well-planned transition to a digital enterprise.

Safe Harbor Statement

Except for the historical information herein, the matters discussed in this release include forward-looking statements. In particular, the forward-looking statements contained in this release include statements about our anticipated financial and operating results for the remainder of fiscal year 2008. When used in this press release, the words: believes, intends, plans, anticipates, expects, estimates, and similar expressions are intended to identify forward-looking statements. Such forward-looking statements are subject to a number of risks, assumptions, and uncertainties that could cause actual results to differ materially which include, but are not limited to, the following: a significant portion of the Company’s quarterly sales are concluded in the last month of the fiscal quarter; the length of sales and delivery cycles; the deferral and/or realization of deferred software license and system revenues according to contract terms; the timing, cost, and success or failure of current and new product and service introductions and product upgrade releases; potential patent infringement claims against AMICAS and the related defense costs; the ability of AMICAS to comply with all government laws, rules, and regulations; and other risks affecting AMICAS’ businesses generally and as set forth in AMICAS’ most recent filings with the Securities and Exchange Commission, including the section entitled “Risk Factors” of our most recent annual report on Form 10-K, and subsequent quarterly reports on Form 10-Q. All forward-looking statements in this release are qualified by these cautionary statements and are made only as of the date of this release. AMICAS is under no obligation (and expressly disclaims any such obligation) to update or alter its forward-looking statements whether as a result of new information, future events, or otherwise. The financial statements and information as of, and for the period ended, September 30, 2008, contained in this press release are subject to review by the Company’s independent registered public accounting firm.

CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited)
(in thousands, except share data)

	September 30,			December 31,
	2008			2007
Assets
Current assets:
Cash and cash equivalents	$	15,244		$	8,536
Marketable securities		38,774			67,071
Accounts receivable, net of allowances of $178 and $231, respectively		10,373			10,483
Prepaid expenses and other current assets		2,294			3,600
Total current assets		66,685			89,690
Property and equipment, less accumulated depreciation and amortization of $7,328 and $6,848, respectively		1,253			1,186
Goodwill		27,313			27,313
Acquired/developed software, less accumulated amortization of $9,624 and $7,992, respectively		6,376			8,008
Other intangible assets, less accumulated amortization of $2,062 and $1,742, respectively		1,338			1,658
Other assets		1,790			586
Total assets	$	104,755		$	128,441
Liabilities and stockholders’ equity
Current liabilities:
Accounts payable and accrued expenses	$	6,922		$	7,094
Accrued employee compensation and benefits		1,504			1,451
Deferred revenue		11,227			10,375
Total current liabilities		19,653			18,920
Unrecognized tax benefits		1,352			1,275
Commitments and contingencies
Stockholders’ equity:
Preferred stock $.001 par value, 2,000,000 shares authorized; none issued		—			—
Common stock $.001 par value, 200,000,000 shares authorized; 51,473,965 and 51,296,823 issued, respectively		51			51
Additional paid-in capital		230,437			229,056
Accumulated other comprehensive income		35			60
Accumulated deficit		(99,851	)		(98,478	)
Treasury stock, at cost, 16,076,951 and 6,824,192 shares		(46,922	)		(22,443	)
Total stockholders’ equity		83,750			108,246
Total Liabilities and Stockholders’ Equity	$	104,755		$	128,441

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
(in thousands, except per share data and footnotes)

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2008			2007			2008			2007
Revenues
Maintenance and services	$	9,616		$	9,739		$	29,921		$	28,530
Software licenses and system sales		2,682			3,562			8,740			9,706
Total revenues	$	12,298			13,301			38,661			38,236
Costs and expenses
Cost of revenues:
Maintenance and services (a)	$	4,579			4,149			13,540			12,335
Software licenses and system sales, including amortization of software costs of $572, $489, $1,632, and $1,468, respectively		1,638			1,971			5,580			5,160
Selling, general, and administrative (b)		4,880			5,290			15,164			16,147
Research and development (c)		2,124			2,112			6,514			6,412
Depreciation and amortization		283			300			835			836
		13,504			13,822			41,633			40,890
Operating loss		(1,206	)		(521	)		(2,972	)		(2,654	)
Interest income		420			992			1,781			2,879
Loss on sale of investments		—			—			(31	)		—
(Loss) income before provision for income taxes		(786	)		471			(1,222	)		225
Provision for income taxes		23			97			151			185
Net (loss) income	$	(809	)	$	374		$	(1,373	)	$	40
(Loss) income per share
Basic:	$	(0.02	)	$	0.01		$	(0.03	)	$	0.00
Diluted:	$	(0.02	)	$	0.01		$	(0.03	)	$	0.00
Weighted average number of shares outstanding
Basic		36,004			44,762			39,976			44,627
Diluted		36,004			45,663			39,976			45,504

(a)	— includes $37,000, $29,000, $107,000, and $77,000 in stock-based compensation expense for the three and nine months ended September 30, 2008, and September 30, 2007, respectively.
(b)	— includes $0.3 million, $0.4 million, $0.6 million, and $1.3 million in stock-based compensation expense for the three and nine months ended September 30, 2008, and September 30, 2007, respectively.
(c)	— includes $107,000, $67,000, $320,000, and $200,000 in stock-based compensation expense for the three and nine months ended September 30, 2008, and September 30, 2007, respectively.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
(in thousands)

	Nine Months Ended
	September 30,
	2008			2007
Operating activities
Net (loss) income	$	(1,373	)	$	40
Adjustments to reconcile net (loss) income to cash provided by operating activities:
Depreciation and amortization		835			837
Provisions for (recoveries from) bad debts		70			84
Loss on disposal of fixed assets		6			—
Amortization of software development costs		1,632			1,468
Non-cash stock compensation expense		1,057			1,548
Changes in operating assets and liabilities:
Accounts receivable		40			(233	)
Computer hardware held for resale, prepaid expenses, and other		103			986
Accounts payable and accrued expenses		(119	)		1,237
Deferred revenue including unearned discount		852			(398	)
Unrecognized tax benefits		76			—
Cash provided by operating activities		3,179			5,569
Investing activities
Purchases of property and equipment		(589	)		(369	)
Purchase of software		—			(2,300	)
Purchases of held-to-maturity securities		(220,708	)		(72,820	)
Maturities of held-to-maturity securities		212,945			67,300
Purchases of available-for-sale securities		(17,590	)		(26,886	)
Sales of available-for-sale securities		53,625			29,540
Cash provided by (used in) investing activities		27,683			(5,535	)
Financing activities
Repurchases of common stock		(24,479	)		—
Exercise of stock options		325			413
Cash (used in) provided by financing activities		(24,154	)		413
Increase in cash and cash equivalents		6,708			447
Cash and cash equivalents at beginning of period		8,536			7,331
Cash and cash equivalents at end of period	$	15,244		$	7,778
Supplemental disclosure of cash paid during the period for:
Income taxes, net of refunds	$	116		$	70
Non-cash investing activities:
Unrealized gain on available-for-sale securities	$	26		$	36

	2008 Projected
	High			Low
Reconciliation of projected net loss to projected EBITDA
Projected net loss	$	(3,500	)	$	(2,800	)
Provision for income taxes		(200	)		(200	)
Interest income		2,100			2,100
Operating loss		(5,400	)		(4,700	)
Non-cash stock compensation expense		1,600			1,600
Depreciation and amortization		1,100			1,100
Amortization of software development costs		2,200			2,200
Projected pro-forma EBITDA	$	(500	)	$	200

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2008			2007			2008			2007
Reconciliation of net (loss) income to EBITDA
Net (loss) income	$	(809	)	$	374		$	(1,373	)	$	40
Provision for income taxes		(23	)		(97	)		(151	)		(185	)
Interest income		420			992			1,781			2,879
Loss on sale of investments		—			—			(31	)		—
Operating loss		(1,206	)		(521	)		(2,972	)		(2,654	)
Non-cash stock compensation expense		438			514			1,057			1,548
Depreciation and amortization		283			300			835			837
Amortization of software development costs		572			489			1,632			1,468
Pro-forma EBITDA	$	87		$	782		$	552		$	1,198