Exhibit 99.1

For more information contact:
Peter Benoist or Frank Sanfilippo (314) 725 5500
Ann Marie Mayuga (314) 485 4390

ENTERPRISE FINANCIAL REPORTS SECOND QUARTER EARNINGS,
CONTINUING RECORD LOAN GROWTH

• Second quarter fully diluted EPS at $0.27 compared to $0.36 in 2007
• Strong organic growth year over year; 23% in loans and 17% in deposits
• As anticipated, nonperforming assets rise to 1.02% of assets, net charge-offs at 0.32% annualized
• Efficiency ratio improves from previous quarter and prior year

St. Louis MO, July 17, 2008. Enterprise Financial Services Corp (NASDAQ: EFSC) reported second quarter 2008 net income of $3.5 million, a decrease of 22% compared to the same period last year. Earnings per fully diluted share were $0.27, down 25% from the comparable 2007 period.

For the first half of 2008, net income totaled $7.1 million versus $7.7 million for the similar period of 2007. Earnings per fully diluted share for 2008 to date were $0.56 compared to $0.62 at mid year 2007, a 10% decrease.

EFSC President and CEO Peter Benoist commented, “Our second quarter results reflect the challenges and the opportunities created by the turmoil in the financial markets. Recent rate reductions have pressured our net interest margin and the slowdown in the homebuilding industry has elevated nonperforming asset and net charge-off levels compared to our historical standards. These conditions are also creating significant competitive opportunities in our markets. We continue growing our loan portfolio and core deposit funding base and attracting new clients at a record pace this year. Robust loan and deposit growth bodes well for future earnings even though the related provision expense is a major factor in our lower current earnings.”

Benoist continued, “Our Wealth Management business, while underperforming relative to prior year periods, has made substantial investments in both personnel and technology which we anticipate will result in significant improvement in second half performance.”

1

Exhibit 99.1

Banking Line of Business

Net interest income rose $1.5 million, or 9%, in the second quarter compared to the same period in 2007 and increased 3% versus the first quarter of 2008. Total portfolio loans at quarter end increased $349 million to $1.85 billion, a 23% increase over one year ago.

Since December 31, 2007, loans increased $208 million. The strong net growth in loans is attributable in part to a more favorable competitive environment, with fewer competitors positioned today to capture new business, resulting in both increased volumes and more favorable pricing. While the attached detail on the loan portfolio shows significant increase in commercial real estate loans, this data is based on collateral codes used for call reports. Using industry codes, 70% of the loan growth in the first six months of 2008 is attributable to commercial and industrial businesses, 13% to commercial real estate clients, 8% to residential construction clients and 6% to commercial construction clients. From a market perspective, approximately 58% of the growth came from St. Louis, with the remainder from Kansas City and Phoenix.

Provision for loan losses was $3.2 million in the second quarter of 2008 compared to $715,000 for the prior year period and $2.3 million in the first quarter of 2008. The provision expense for the second quarter was driven equally by strong loan growth and adverse changes in risk ratings on several credits. The allowance for loan losses totaled 1.30% of portfolio loans and 182% of nonperforming loans at June 30, 2008 compared to 1.31% and 156%, respectively, at June 30, 2007. At March 31, 2008, the allowance for loan losses totaled 1.29% of portfolio loans and 239% of nonperforming loans.

Nonperforming loans were $13.2 million at June 30, 2008 compared to $12.7 million at June 30, 2007 and $9.3 million at March 31, 2008. Excluding nonperforming loans, delinquency rates are higher than first quarter, but are still at manageable levels. Nonperforming assets, which include Other real estate, totaled 1.02% of total assets for the second quarter versus 0.75% for the second quarter of 2007 and 0.83% for the first quarter of 2008.

Approximately $5.2 million of nonperforming loans and $8.9 million of Other real estate are represented largely by residential construction developments, primarily in Kansas City. In total, 63% of nonperforming assets are related to residential development. The largest single nonperforming loan is for a $4.9 million commercial retail development in Northwest Arkansas and the largest Other real estate property is a $3.4 million residential development in Kansas City, both of which we believe are appropriately valued.

Second quarter net charge-offs of $1.4 million represented 0.32% of average portfolio loans on an annualized basis, compared to 0.06% for the second quarter of 2007 and 0.40% for the first quarter of 2008. Three residential credits that were specifically reserved for at March 31, 2008 represent $1.3 million, or 91%, of the second quarter net charge-offs.

2

Exhibit 99.1

Steve Marsh, Chairman and CEO of Enterprise Bank & Trust, remarked, “Our nonperforming asset and net charge-off ratios are not out of line with our expectation as we progress through this credit cycle. We are managing the process aggressively, as illustrated over the past few quarters by the progression of nonperforming loans to other real estate owned and, ultimately, to disposition of the real estate. In fact, year to date the Company has disposed of $4.0 million of Other real estate at a net gain of $342,000.”

Marsh continued, “Our credit issues remain concentrated in the residential homebuilding sector. That industry remains under stress and these conditions are not likely to abate quickly, although it’s important to note that residential homebuilding represents only 11% of our total loan portfolio. While we’ve also seen stress in parts of the commercial retail-real estate segment and in trucking-related businesses, most other industry sectors in our markets remain relatively healthy, with some doing quite well.”

Total deposits increased 17% from June 30, 2007 and 5% from March 31, 2008. Non-interest bearing deposits represented 14% of total deposits at June 30, 2008. The Company remains predominantly core-funded. As a result of strong loan growth in the first six months of 2008, which is seasonally a slower period of deposit growth, we have utilized somewhat higher levels of wholesale funding. Nonetheless, brokered deposits represented less than 16% of total deposits at June 30, 2008.

Tax-equivalent net interest margin for the second quarter was 3.56%, a decrease of 0.25% from the year earlier period, but only 0.07% down from the first quarter level. Net interest margin has been compressed largely due to sharply reduced short-term rates from a year ago. However, the net interest spread between interest bearing assets and interest-bearing liabilities has increased 0.11% from 3.09% to 3.20% on a year over year basis and increased 0.05% on a linked quarter basis. Through aggressive repricing initiatives, the Company has been able to reduce its interest bearing liability costs more than enough to offset lower earning asset yields.

Wealth Management Line of Business

Fee income from the Wealth Management line of business, in the second quarter totaled $2.7 million, an $800,000 or 23% decrease, from the year ago period. For the six months ended June 30, 2008, Wealth Management fee income totaled $6.3 million, down $100,000 or 2%, for the same period in 2007.

Trust revenues for the second quarter and year to date have been negatively impacted by declining market values of assets under management and client attrition related to advisor turnover experienced in the first quarter. Fiduciary revenues continue to grow modestly as new business volumes have been steady.

Millennium Brokerage Group revenues continue to be adversely impacted by declining sales margins due to a shifting carrier mix and higher producer payouts. Management is pursuing strategies to increase producer sales volumes and renegotiate higher carrier payouts. The second half of the year has historically generated the majority of annual revenues for Millennium.

3

Exhibit 99.1

Reported fee income from state tax credit brokerage activities during the quarter was negative due to a $135,000 fair value reduction under FAS 159 on the $38 million in tax credits held for sale at June 30, 2008. Seasonality was also a factor, as the tax credits are primarily sold in the first and fourth quarters of the year. As allowed under FAS 159, during the third quarter the Company intends to elect the fair value option for a new liability with similar cash flows to help offset the fair value adjustment on the tax credit assets.

Expenses in Wealth Management were essentially flat in the second quarter of 2008 versus 2007 but increased just over $400,000 higher on a year to date basis due primarily to the restructure of Millennium’s compensation for principals as part of the buyout of the remaining minority interest on December 31, 2007.

Overall, the Wealth Management segment posted a $430,000 pre-tax loss for the quarter ended June 30, 2008 versus an $880,000 pre-tax profit in the same quarter of 2007. Year to date the segment recorded a $119,000 pre-tax loss versus a $993,000 pre-tax profit in the same period of 2007.

Other business results

During the quarter, the Company filed an application for a new Arizona state bank charter with locations in central and west Phoenix. Enterprise opened a loan production office in Phoenix during the fourth quarter of 2007 and had approximately $20 million in loans outstanding at June 30, 2008.

Strong asset growth has outpaced reported earnings for the first half of the year due to the related provision expense and compressed margins in both lines of business. To support continuing growth and the anticipated charter approvals for our Arizona bank and national Trust company by the end of the year, the Company expects to add $30 million or more in regulatory capital in the form of either subordinated debt, trust preferred, REIT preferred or a combination thereof.

Also during the second quarter, Enterprise converted the Claycomo, Missouri branch of its Great American Bank subsidiary to an Enterprise Bank & Trust branch through the purchase and assumption of the branch’s assets and liabilities. This transaction is part of the Company’s previously announced agreement to sell its Great American Bank charter and its other location in Desoto, Kansas. The sale of that location and the bank charter is scheduled to be completed in the third quarter.

The Company’s efficiency ratio improved to 59.9% in the second quarter of 2008 from 61.8% a year ago. Noninterest expenses in the second quarter of 2008 increased a modest 2.9% as compared to the same quarter in 2007. On a linked quarter basis, noninterest expenses in the second quarter of 2008 declined 8% due to savings in salaries and benefits, rental expense and real estate owned expenses.

4

Exhibit 99.1

Benoist concluded, “Enterprise’s focus on a diverse base of private businesses and their owner families, coupled with our longstanding, strong credit management processes continue to serve us well in this challenging environment. Managing through this credit cycle is clearly the paramount issue in the banking industry today – and it’s the top priority in our Company also - but at the same time we’re not losing sight of the opportunities in front of us to continue to build long-term value for our shareholders.”

Enterprise Financial operates commercial banking and wealth management businesses in metropolitan St. Louis and Kansas City and a loan production office in Phoenix. Enterprise is primarily focused on serving the needs of privately held businesses, their owner families, executives and professionals.

#                  #                  #

Readers should note that in addition to the historical information contained herein, this press release contains forward-looking statements, which are inherently subject to risks and uncertainties that could cause actual results to differ materially from those contemplated from such statements. We use the words “expect” and “intend” and variations of such words and similar expressions in this communication to identify such forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to, burdens imposed by federal and state regulations of banks, credit risk, exposure to local and national economic conditions, risks associated with rapid increase or decrease in prevailing interest rates, effects of mergers and acquisitions, effects of critical accounting policies and judgments, legal and regulatory developments and competition from banks and other financial institutions, as well as other risk factors described in Enterprise Financial’s 2007 Annual Report on Form 10-K. Forward-looking statements speak only as of the date they are made, and the Company undertakes no obligation to update them in light of new information or future events.

5

ENTERPRISE FINANCIAL SERVICES CORP
CONSOLIDATED FINANCIAL SUMMARY
(unaudited)

(In thousands, except per share data)	For the Quarter Ended						For the Six Months Ended
	Jun 30,			Jun 30,			Jun 30,			Jun 30,
INCOME STATEMENTS	2008			2007			2008			2007
Total interest income	$	29,283		$	30,946		$	59,531		$	58,796
Total interest expense		12,481			15,821			26,589			29,750
Net interest income		16,802			15,125			32,942			29,046
Provision for loan losses		3,200			715			5,525			1,565
Net interest income after provision for loan losses		13,602			14,410			27,417			27,481
NONINTEREST INCOME
Wealth Management revenue		2,682			3,458			5,266			6,421
Deposit service charges		1,202			804			2,139			1,463
Gain (loss) on sale of other real estate		351			(8	)		342			(12	)
(Loss) gain on sale of state tax credits		(29	)		-			984			-
Gain on sale of securities		73			-			73			-
(Loss) gain on sale of branch		(19	)		-			560			-
Other income		184			652			616			931
Total noninterest income		4,444			4,906			9,980			8,803
NONINTEREST EXPENSE
Salaries and benefits		7,575			7,141			15,914			14,449
Occupancy		977			1,025			2,060			1,903
Furniture and equipment		355			370			719			686
Other		3,816			3,834			7,863			7,193
Total noninterest expense		12,723			12,370			26,556			24,231
Minority interest in net income of consolidated subsidiary		-			157			-			-
Income before income tax		5,323			7,103			10,841			12,053
Income taxes		1,823			2,588			3,778			4,380
Net income	$	3,500		$	4,515		$	7,063		$	7,673
Basic earnings per share	$	0.28		$	0.37		$	0.57		$	0.63
Diluted earnings per share	$	0.27		$	0.36		$	0.56		$	0.62
Return on average assets		0.67	%		1.03	%		0.70	%		0.92	%
Return on average equity		7.77	%		11.20	%		7.95	%		10.14	%
Efficiency ratio		59.88	%		61.75	%		61.87	%		64.02	%
Noninterest expense to average assets		2.43	%		2.83	%		2.62	%		2.91	%
YIELDS (fully tax equivalent)
Loans		6.30	%		7.98	%		6.60	%		7.96	%
Securities		4.60	%		4.50	%		4.71	%		4.40	%
Federal funds sold		1.85	%		5.49	%		2.88	%		5.47	%
Yield on earning assets		6.17	%		7.72	%		6.46	%		7.69	%
Interest bearing deposits		2.78	%		4.47	%		3.11	%		4.45	%
Subordinated debt		5.66	%		7.19	%		6.18	%		7.20	%
Borrowed funds		3.44	%		5.04	%		3.60	%		5.02	%
Cost of paying liabilities		2.97	%		4.63	%		3.29	%		4.59	%
Net interest spread		3.20	%		3.09	%		3.17	%		3.10	%
Net interest rate margin		3.56	%		3.81	%		3.60	%		3.83	%

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     ENTERPRISE FINANCIAL SERVICES CORP
CONSOLIDATED FINANCIAL SUMMARY (cont.)
(unaudited)

(In thousands)
	Jun 30,		Mar 31,		Dec 31,		Sep 30,		Jun 30,
BALANCE SHEETS	2008		2008		2007		2007		2007
ASSETS
Cash and due from banks	$	67,661	$	64,108	$	76,265	$	47,593	$	45,081
Federal funds sold		15,630		954		75,665		2,585		2,059
Interest-bearing deposits		349		6,435		1,719		1,100		1,021
Debt and equity investments		120,072		116,810		83,333		122,204		111,617
Loans held for sale		1,666		3,422		3,420		1,117		3,840
Portfolio loans		1,849,415		1,726,455		1,641,432		1,558,885		1,500,512
Less allowance for loan losses		24,011		22,249		21,593		19,754		19,703
Net loans		1,825,404		1,704,206		1,619,839		1,539,131		1,480,809
Other real estate		9,294		7,736		2,963		857		441
Premises and equipment, net		25,238		24,775		22,223		22,487		22,801
State tax credits, held for sale		37,882		27,309		23,149		-		-
Goodwill		57,910		58,331		57,177		55,661		54,841
Core deposit intangible		2,729		2,887		3,330		3,511		3,693
Other amortizing intangibles		2,301		2,512		2,723		2,952		3,180
Other assets		31,582		28,393		27,312		29,061		23,929
Total assets	$	2,197,718	$	2,047,878	$	1,999,118	$	1,828,259	$	1,753,312
LIABILITIES AND SHAREHOLDERS' EQUITY
Non-interest bearing deposits	$	240,148	$	232,121	$	278,313	$	212,903	$	215,771
Interest bearing deposits		1,429,598		1,358,588		1,306,699		1,233,532		1,212,353
Total deposits		1,669,746		1,590,709		1,585,012		1,446,435		1,428,124
Subordinated debentures		56,807		56,807		56,807		56,807		56,807
FHLB advances		203,043		154,405		152,901		131,746		88,192
Other borrowings		72,886		53,508		16,680		10,613		7,593
Other liabilities		12,335		14,212		14,569		13,415		9,527
Total liabilities		2,014,817		1,869,641		1,825,969		1,659,016		1,590,243
Shareholders' equity		182,901		178,237		173,149		169,243		163,069
Total liabilities and shareholders' equity	$	2,197,718	$	2,047,878	$	1,999,118	$	1,828,259	$	1,753,312

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     ENTERPRISE FINANCIAL SERVICES CORP
CONSOLIDATED FINANCIAL SUMMARY (cont.)
(unaudited)

(In thousands, except per share data)	For the Quarter Ended
	Jun 30,			Mar 31,			Dec 31,			Sep 30,			Jun 30,
	2008			2008			2007			2007			2007
EARNINGS SUMMARY
Net interest income	$	16,802		$	16,137		$	16,203		$	15,805		$	15,125
Provision for loan losses		3,200			2,325			2,450			600			715
Wealth Mangement revenue		2,682			2,583			4,064			3,495			3,458
Noninterest income		1,762			2,955			2,166			1,143			1,448
Noninterest expense		12,723			13,832			13,083			12,202			12,370
Minority interest in net income of consolidated subsidiary		-			-			-			-			157
Income before income tax		5,323			5,518			6,900			7,641			7,103
Net income		3,500			3,563			4,906			4,999			4,515
Diluted earnings per share	$	0.27		$	0.28		$	0.39		$	0.40		$	0.36
Return on average equity		7.77	%		8.13	%		11.28	%		11.85	%		11.20	%
Net interest rate margin (fully tax equivalized)		3.56	%		3.63	%		3.80	%		3.87	%		3.81	%
Efficiency ratio		59.88	%		63.82	%		58.32	%		59.69	%		61.75	%
MARKET DATA
Book value per share	$	14.45		$	14.27		$	13.96		$	13.66		$	13.20
Tangible book value per share	$	9.48		$	9.17		$	8.86		$	8.65		$	8.20
Market value per share	$	18.85		$	25.00		$	23.81		$	24.34		$	24.86
Period end common shares outstanding		12,654			12,487			12,406			12,388			12,354
Average basic common shares		12,545			12,441			12,387			12,380			12,346
Average diluted common shares		12,760			12,675			12,676			12,652			12,692
ASSET QUALITY
Net charge-offs	$	1,439		$	1,668		$	611		$	549		$	232
Nonperforming loans	$	13,180		$	9,307		$	12,720		$	8,542		$	12,661
Nonperforming loans to total loans		0.71	%		0.54	%		0.77	%		0.55	%		0.84	%
Nonperforming assets to total assets		1.02	%		0.83	%		0.78	%		0.51	%		0.75	%
Allowance for loan losses to total loans		1.30	%		1.29	%		1.32	%		1.27	%		1.31	%
Net charge-offs to average loans (annualized)		0.32	%		0.40	%		0.15	%		0.14	%		0.06	%
CAPITAL
Average equity to average assets		8.62	%		8.92	%		9.21	%		9.40	%		9.22	%
Tier 1 capital to risk-weighted assets		8.76	%		9.15	%		9.32	%		9.85	%		9.82	%
Total capital to risk-weighted assets		9.96	%		10.36	%		10.54	%		11.05	%		11.09	%
Tangible equity to tangible assets		5.62	%		5.77	%		5.68	%		6.07	%		5.99	%
AVERAGE BALANCES
Portfolio loans	$	1,790,491		$	1,687,316		$	1,583,325		$	1,526,259		$	1,492,573
Earning assets		1,922,309			1,810,384			1,719,825			1,645,697			1,622,139
Total assets		2,102,582			1,974,590			1,873,915			1,780,239			1,754,297
Deposits		1,600,805			1,530,158			1,511,476			1,453,497			1,426,002
Shareholders' equity		181,274			176,170			172,563			167,310			161,663
LOAN PORTFOLIO
Commercial and industrial	$	510,377		$	487,289		$	476,184		$	416,715		$	391,237
Commercial real estate		835,688			735,087			690,868			703,772			681,735
Construction real estate		284,556			285,966			266,111			252,476			247,722
Residential real estate		193,630			189,549			170,510			155,489			149,182
Consumer and other		25,164			28,564			37,759			30,433			30,636
Total loan portfolio	$	1,849,415		$	1,726,455		$	1,641,432		$	1,558,885		$	1,500,512
DEPOSIT PORTFOLIO
Noninterest-bearing accounts	$	240,148		$	232,121		$	278,313		$	212,903		$	215,771
Interest-bearing transaction accounts		134,659			136,009			131,141			120,069			128,808
Money market and savings accounts		680,635			724,725			682,920			596,226			552,678
Certificates of deposit		614,304			497,854			492,638			517,237			530,867
Total deposit portfolio	$	1,669,746		$	1,590,709		$	1,585,012		$	1,446,435		$	1,428,124

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ENTERPRISE FINANCIAL SERVICES CORP
CONSOLIDATED FINANCIAL SUMMARY (cont.)
(unaudited)

(In thousands)	For the Quarter Ended
	Jun 30,			Mar 31,			Dec 31,			Sep 30,			Jun 30,
	2008			2008			2007			2007			2007
YIELDS (fully tax equivalent)
Loans		6.30	%		6.93	%		7.65	%		7.96	%		7.98	%
Securities		4.60	%		4.84	%		4.87	%		4.67	%		4.50	%
Federal funds sold		1.85	%		3.32	%		4.23	%		5.53	%		5.49	%
Yield on earning assets		6.17	%		6.77	%		7.42	%		7.73	%		7.72	%
Interest bearing deposits		2.78	%		3.46	%		4.10	%		4.44	%		4.47	%
Borrowed funds		3.44	%		3.82	%		4.54	%		5.00	%		5.04	%
Subordinated debt		5.66	%		6.71	%		7.24	%		7.20	%		7.19	%
Cost of paying liabilities		2.97	%		3.62	%		4.26	%		4.59	%		4.63	%
Net interest spread		3.20	%		3.15	%		3.16	%		3.14	%		3.09	%
Net interest rate margin		3.56	%		3.63	%		3.80	%		3.87	%		3.81	%
WEALTH MANAGEMENT
Trust Assets under management	$	986,717		$	1,046,390		$	1,098,110		$	1,106,214		$	1,111,042
Trust Assets under administration		1,532,559			1,633,195			1,696,303			1,734,761			1,742,426

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