<SEC-DOCUMENT>0001025835-22-000022-index.html : 20220322
<SEC-HEADER>0001025835-22-000022.hdr.sgml : 20220322
<ACCEPTANCE-DATETIME>20220322163249
ACCESSION NUMBER:		0001025835-22-000022
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		4
CONFORMED PERIOD OF REPORT:	20220322
FILED AS OF DATE:		20220322
DATE AS OF CHANGE:		20220322

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ENTERPRISE FINANCIAL SERVICES CORP
		CENTRAL INDEX KEY:			0001025835
		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
		IRS NUMBER:				431706259
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-15373
		FILM NUMBER:		22760009

	BUSINESS ADDRESS:	
		STREET 1:		150 NORTH MERAMEC
		STREET 2:		150 NORTH MERAMEC
		CITY:			CLAYTON
		STATE:			MO
		ZIP:			63105
		BUSINESS PHONE:		3147255500

	MAIL ADDRESS:	
		STREET 1:		150 NORTH MERAMEC
		STREET 2:		150 NORTH MERAMEC
		CITY:			CLAYTON
		STATE:			MO
		ZIP:			63105

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ENTERBANK HOLDINGS INC
		DATE OF NAME CHANGE:	19961024
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>efsc2021def14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: efsc2021def14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>nisignaturea03.jpg
<DESCRIPTION>SIGNATURE
<TEXT>
Document 2 - file: nisignaturea03.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>proxycard1final_pagex1.jpg
<DESCRIPTION>PROXYCARDPAGE1
<TEXT>
Document 3 - file: proxycard1final_pagex1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>proxycard1final_pagex2.jpg
<DESCRIPTION>PROXYCARDPAGE2
<TEXT>
Document 4 - file: proxycard1final_pagex2.jpg

</DOCUMENT>
</SEC-DOCUMENT>