-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 AAgKsm5jAL9L7zfTdnuF/kFx6T+TjhyQCSn2zo1ZTfoH4dstgkPGX+Ttq99i/pvS
 IIYwe2McS0HOQi6Tf2djAg==

<SEC-DOCUMENT>0001104659-05-009310.txt : 20050303
<SEC-HEADER>0001104659-05-009310.hdr.sgml : 20050303
<ACCEPTANCE-DATETIME>20050303124846
ACCESSION NUMBER:		0001104659-05-009310
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050222
FILED AS OF DATE:		20050303
DATE AS OF CHANGE:		20050303

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			GRADY DANIEL J
		CENTRAL INDEX KEY:			0001197756

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-12531
		FILM NUMBER:		05656970

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		3032797900

	MAIL ADDRESS:	
		STREET 1:		ISONICS CORP
		STREET 2:		5906 MCINTYRE STREET
		CITY:			GOLDEN
		STATE:			CO
		ZIP:			80403

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ISONICS CORP
		CENTRAL INDEX KEY:			0001023966
		STANDARD INDUSTRIAL CLASSIFICATION:	CHEMICALS & ALLIED PRODUCTS [2800]
		IRS NUMBER:				770338561
		STATE OF INCORPORATION:			CA
		FISCAL YEAR END:			0430

	BUSINESS ADDRESS:	
		STREET 1:		5906 MCINTYRE STREET
		CITY:			GOLDEN
		STATE:			CO
		ZIP:			80403
		BUSINESS PHONE:		3032797900

	MAIL ADDRESS:	
		STREET 1:		5906 MCINTYRE STREET
		CITY:			GOLDEN
		STATE:			CO
		ZIP:			80403
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>a4a.xml
<DESCRIPTION>4/A
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2005-02-22</periodOfReport>

    <dateOfOriginalSubmission>2005-02-24</dateOfOriginalSubmission>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001023966</issuerCik>
        <issuerName>ISONICS CORP</issuerName>
        <issuerTradingSymbol>ISON</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001197756</rptOwnerCik>
            <rptOwnerName>GRADY DANIEL J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ISONICS CORPORATION</rptOwnerStreet1>
            <rptOwnerStreet2>5906 MCINTYRE STREET</rptOwnerStreet2>
            <rptOwnerCity>GOLDEN</rptOwnerCity>
            <rptOwnerState>CO</rptOwnerState>
            <rptOwnerZipCode>80403</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Employee</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option F3</value>
                <footnoteId id="F3"/>
                <footnoteId id="F4"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.06</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2001-11-13</value>
            </exerciseDate>
            <expirationDate>
                <value>2011-11-13</value>
                <footnoteId id="F8"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>100000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>100000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option F3</value>
                <footnoteId id="F3"/>
                <footnoteId id="F6"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.20</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2003-12-16</value>
            </exerciseDate>
            <expirationDate>
                <value>2013-12-16</value>
                <footnoteId id="F8"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>50000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>50000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F3">This transaction is exempt from Section 16 pursuant to Rule 16b-3(d).</footnote>
        <footnote id="F4">20,000 shares vest on November 13, 2001 and 20,000 shares vest on November 13th of each of the years 2002, 2003, 2004, and 2005.  The grant of options was subject to acceptance by the reporting person.  The resporting person accepted the options on December 19, 2001.</footnote>
        <footnote id="F6">Options granted by resolution of the Board of Directors pursuant to the 1996 Executives' Equity Incentive Plan.  The grant of the options is subject to acceptance by the reporting person, which acceptance was received on December 16, 2003.</footnote>
        <footnote id="F8">Correction to expiration date.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Daniel J. Grady</signatureName>
        <signatureDate>2005-03-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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