-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, BvtL7BA0pRLlEh5xefsOSQ5zbiC1fktmThLa5bMM9wTKyUKLnLJjihEBgQGvgCaF D7PJtloPZD5lFDmTzPmkiA== 0001144204-06-029351.txt : 20060721 0001144204-06-029351.hdr.sgml : 20060721 20060721170114 ACCESSION NUMBER: 0001144204-06-029351 CONFORMED SUBMISSION TYPE: 6-K PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20060719 FILED AS OF DATE: 20060721 DATE AS OF CHANGE: 20060721 FILER: COMPANY DATA: COMPANY CONFORMED NAME: XTL BIOPHARMACEUTICALS LTD CENTRAL INDEX KEY: 0001023549 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: 6-K SEC ACT: 1934 Act SEC FILE NUMBER: 000-51310 FILM NUMBER: 06974674 BUSINESS ADDRESS: STREET 1: KIRYAT WEIZMANN BUILDING 3 CITY: REHOVOT76100 ISRAEL STATE: L3 MAIL ADDRESS: STREET 1: KIRYAT WEIZMANN BUILDING 3 CITY: REHOVOT76100 ISRAEL STATE: L3 ZIP: 00000 6-K 1 v047940_6k.htm
 
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form 6-K

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16
of the Securities Exchange Act of 1934

For July 19, 2006

Commission File Number: 000-51310

XTL Biopharmaceuticals Ltd.
(Translation of registrant's name into English)

750 Lexington Avenue, 20th Floor
New York, New York 10022
(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.
 
 
Form 20-F x
Form 40-F o
  
 
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ____

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ____

Indicate by check mark whether by furnishing the information contained in this Form, the registrant is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

 
Yes o
No x
  
 
If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82- N/A  

 
 
 
 

XTL Provides Update on HepeX-B Program

New York, NY, July 19, 2006 - XTL Biopharmaceuticals, Ltd. (NASDAQ: XTLB, LSE: XTL, TASE: XTL) provided today an update on HepeX-B - a drug candidate for the prevention of re-infection with Hepatitis B following liver transplantation.

HepeX-B™ was discovered and developed by XTL, and was licensed to Cubist Pharmaceuticals in June 2004.

In December 2005, Cubist announced the positive results of a Phase 2B study with HepeX-B, based on which Cubist planned to meet with the FDA to discuss a proposed Phase 3 trial design.

During its quarterly investor conference call held earlier today, Cubist reported that the FDA direction on the regulatory pathway for approval creates both operational and economic challenges. The size of the safety population the FDA is looking for translates to an extremely lengthy development timeline, as there are only about 500 liver transplants due to hepatitis B each year--across the U.S. and Europe. At this point, Cubist has decided not to make any further investment in the HepeX-B program while the company evaluates strategic options for HepeX-B.

Ron Bentsur, XTL’s CEO, commented: “While we are disappointed, we consider the economic impact of Cubist’s decision on XTL to be nominal as due to the size of the market for HepeX-B, we do not believe that the potential royalties from Cubist constituted a value driver for XTL. The key value drivers for XTL remain the two clinical programs in Hepatitis C, the pre-clinical program for Hepatitis C, and our in-licensing program.”

ABOUT XTL BIOPHARMACEUTICALS, LTD.
 
XTLbio is engaged in the acquisition, development and commercialization of therapeutics for the treatment of infectious diseases, with a focus on hepatitis C. XTLbio is developing XTL-2125 - a small molecule, non-nucleoside inhibitor of the hepatitis C virus polymerase - presently in Phase 1 clinical trials in patients with chronic hepatitis C. XTLbio is also developing XTL-6865 - a combination of two monoclonal antibodies against the hepatitis C virus - presently in Phase 1 clinical trials in patients with chronic hepatitis C. XTLbio’s hepatitis C pipeline also includes several families of pre-clinical hepatitis C small molecules. XTLbio is publicly traded on the Nasdaq, London, and Tel-Aviv Stock Exchanges (NASDAQ: XTLB; LSE: XTL; TASE: XTL).

Contact:
 
   
XTL Biopharmaceuticals Ltd.
Ron Bentsur, Chief Executive Officer
212-531-5960
rbentsur@xtlbio.com
     
   
Redington, Inc.
Thomas Redington
203.222.7399
212.926.1733
 
 
 

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
     
   
  XTL BIOPHARMACEUTICALS LTD.
 
 		  
 		  
 
Date: July 20, 2006 By:   /s/ Ron Bentsur
 
Ron Bentsur
 
Chief Executive Officer
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