8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

CURRENT REPORT ON FORM 8K

PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

April 18, 2011

(Date of the earliest event reported)

Simulations Plus, Inc.

(Exact name of registrant as specified in its charter)

California	001-32046	95-4595609
(State or other jurisdiction of incorporation)	(Commission File Number)	(I.R.S. Employer Identification No.)

42505 10th Street West, Lancaster, California 93534-7059

(Address of principal executive offices) (Zip Code)

661-723-7723

Registrant's telephone number, including area code

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14z-12 under Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under Exchange Act (17 CFR 240.13e-4(c))

Item 8.01Other Events

On April 18, 2011, Simulations Plus, Inc., a California corporation (the "Company"), held a conference call reporting its financial results for the second fiscal quarter ended February 28, 2011.

The PowerPoint slides, which were used for this Conference Call, are attached herein as an exhibit.

This report on Form 8-K (the "Report"), including the disclosures set forth herein, contains certain forward-looking statements that involve substantial risks and uncertainties. When used herein, the terms "anticipates," "expects," "estimates," "believes" and similar expressions, as they relate to us or our management, are intended to identify such forward-looking statements.

Forward-looking statements in this Report or hereafter, including in other publicly available documents filed with the Securities and Exchange Commission (the "Commission"), reports to the stockholders of Simulations Plus, Inc., a California corporation (the "Company" or "us," "our" or "we") and other publicly available statements issued or released by us involve known and unknown risks, uncertainties and other factors which could cause our actual results, performance (financial or operating) or achievements to differ from the future results, performance (financial or operating) or achievements expressed or implied by such forward-looking statements. Such future results are based upon management's best estimates based upon current conditions and the most recent results of operations. These risks include, but are not limited to, the risks set forth herein and in such other documents filed with the Commission, each of which could adversely affect our business and the accuracy of the forward-looking statements contained herein. Our actual results, performance or achievements may differ materially from those expressed or implied by such forward-looking statements.

Item 9.01Financial Statements and Exhibits

(d) Exhibits

 99.1PowerPoint presentation at the Conference Call on April 18, 2011.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	SIMULATIONS PLUS, INC.
Dated: April 18, 2011	By:	/s/ Momoko Beran
		Momoko Beran
		Chief Financial Officer

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EX-99.1

Exhibit 99.1

Simulations Plus, Inc.

(NASDAQ:SLP)

Second Quarter FY 2011

Conference Call and Webinar

April 18, 2011

With the exception of historical information, the matters discussed in this
presentation are forward looking statements that involve a number of risks
and uncertainties. The actual results of the Company could differ
significantly from those statements. Factors that could cause or contribute
to such differences include, but are not limited to: continuing demand for
the Company’s products, competitive factors, the Company’s ability to
finance future growth, the Company’s ability to produce and market new
products in a timely fashion, the Company’s ability to continue to attract
and retain skilled personnel, and the Company’s ability to sustain or
improve current levels of productivity. Further information on the
Company’s risk factors is contained in the Company’s quarterly and
annual reports and filed with the Securities and Exchange Commission.

Safe Harbor Statement

•2Q11 compared to 2Q10:

–14th consecutive profitable quarter

–2Q11 sales up 13.5% to Record $3.35 MM from $2.95 MM

–Net Income up 41.6%

–Pharmaceutical segment sales up 17.7%

–Words+ subsidiary sales up 0.7%

•6moFY11 compared to 6moFY10:

–Net Income up 37.7% to $1.475 million from $1.071 million

–Pharmaceutical segment sales up 17.9%

–Words+ subsidiary sales up 4.4%

–Diluted earnings per share up 39.1% to $0.09 from $0.06.

•Strong balance sheet:

–Cash $8.76 MM at 2/28/11, after using cash of $4.2 million to
repurchase more than 2,022,000 shares over the past two years

–Shareholders’ equity decreased 3% to $12.66 million from $13.05
million at 9/1/10 due to cash used for share repurchases

–No debt

SLP 2Q11 Highlights
Three months ended 2/28/11

Consolidated Revenue

Revenue History

Pharmaceutical Growth

Gross Margin (consolidated)

75.6%

78.9%

78.8%

70.4%

73.8%

74.4%

80.0%

67.9%

75.0%

76.3%

77.6%

75.6%

73.6%

77.6%

Income Before Taxes

Net Income

$243K

$565K

$764K

$165K

$312K

$368K

$569K

$163K

$430K

$641K

$740K

$345K

$567K

$907K

Consolidated Income Statement

($ millions)

	2Q11	2Q10
Pharmaceutical software and services revenue	2.621	2.227
Words+ revenue	0.728	0.723
Consolidated revenue	3.349	2.950
Gross profit	2.601	2.249
Gross profit margin	77.6%	76.3%
SG&A	0.980	1.089
R&D	0.255	0.252
Total operating expenses	1.235	1.341
Income before income taxes	1.394	0.974
Net income	0.907	0.641
Earnings per share (diluted)	0.056	0.039

Select Balance Sheet Items

($ millions)

	February 28, 2011	February 28, 2010
Cash and cash equivalents	$8.759	$8.641
Total current assets	12.403	11.448
Total assets	$14.785	$13.613
Total current liabilities	1.460	1.294
Total liabilities	2.130	2.152
Shareholders’ equity	12.655	11.461
Total liabilities and shareholders’ equity	14.785	13.613

Share Repurchase Program

•The board of directors approved a second share repurchase
program beginning February 2010 for one year (Phase II)

•The Phase II program authorized repurchase of up to
1,000,000 shares through February 2011

•The repurchase program is now complete

•Over both Phase I and Phase II, the company repurchased 2,023,000
shares at an average price of $2.05 per share

•The board of directors could authorize another phase of share
repurchases at any time

•As of today the board has no plans for doing so

Marketing and Sales Program

•Fundamental industry shift continues

–Pharma increasingly utilizing simulation software and modeling tools
to increase productivity - steady stream of scientific meetings

–Software tools are always evolving, and as the technology advances,
new capabilities attract new users, such as the improved and
expanded structure-property models in ADMET Predictor 5.5; the drug
-drug interaction, ocular and nasal/pulmonary delivery capabilities in
GastroPlus 7.0; and the powerful de novo molecule design capabilities
in MedChem Studio, and our fantastic new MedChem
Designer/ADMET Predictor combination.

–Our team continues its prolific generation of scientific papers, posters,
and podium presentations, with > 30 in the past year

–Collaborations/Consulting/Grants

–We have now completed our SBIR grant and all of the large funded
collaborations that contributed to revenues and earnings for several
years; however study contracts continue to be strong with a number of
customers coming back for repeated consulting work.

–We recently signed a 5-year collaboration with the FDA Center for
Food Safety and Applied Nutrition to build toxicity models with ADMET
Predictor/Modeler™ for food additives and contaminants

–We recently formed a second studies team for informatics to address
the need for consulting work in that area (ADMET Predictor &
MedChem Studio).

MedChem Designer - new and powerful!

Make copies of a

starting molecule,
modify them,
then click on the
AP button and see
>120 predicted
properties for
each of them.
Decide in a few
seconds whether
you want to keep
any of them or try
different changes
to the structure.

Summary

•For the trailing twelve months through February 28:

–Revenues = $11.486 million

–Net Income = $2.542 million (22.3%)

–Earnings/share = $0.16 (16.218 million shares)

•Simulations Plus is globally recognized as a leader in our
respective market niches, with an outstanding reputation for
scientific expertise, technological innovation, and strong
customer support.

•We are expanding our Life Sciences team to promote faster
development of new products and services as well as to
reinforce marketing and sales efforts.

Q&A