8-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

January 14, 2011

(Date of the earliest event reported)

Simulations Plus, Inc.

(Exact name of registrant as specified in its charter)

California	001-32046	95-4595609
(State or other jurisdiction of incorporation)	(Commission File Number)	(I.R.S. Employer Identification No.)

42505 10th Street West, Lancaster, California 93534-7059

(Address of principal executive offices) (Zip Code)

661-723-7723

Registrant's telephone number, including area code

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14z-12 under Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under Exchange Act (17 CFR 240.14d-2(b))

o re-commencement communications pursuant to Rule 13e-4(c) under Exchange Act (17 CFR 240.13e-4(c))

Item 8.01     Other Events

On January 14, 2011, Simulations Plus, Inc., a California corporation (the "Company"), held a conference call reporting its financial result for the first fiscal quarter ended November 30, 2010.

The PowerPoint slides, which were used for this Conference Call, are attached herein as an exhibit.

This report on Form 8-K (the "Report"), including the disclosures set forth herein, contains certain forward-looking statements that involve substantial risks and uncertainties. When used herein, the terms "anticipates," "expects," "estimates," "believes" and similar expressions, as they relate to us or our management, are intended to identify such forward-looking statements.

Forward-looking statements in this Report or hereafter, including in other publicly available documents filed with the Securities and Exchange Commission (the "Commission"), reports to the stockholders of Simulations Plus, Inc., a California corporation (the "Company" or "us," "our" or "we") and other publicly available statements issued or released by us involve known and unknown risks, uncertainties and other factors which could cause our actual results, performance (financial or operating) or achievements to differ from the future results, performance (financial or operating) or achievements expressed or implied by such forward-looking statements. Such future results are based upon management's best estimates based upon current conditions and the most recent results of operations. These risks include, but are not limited to, the risks set forth herein and in such other documents filed with the Commission, each of which could adversely affect our business and the accuracy of the forward-looking statements contained herein. Our actual results, performance or achievements may differ materially from those expressed or implied by such forward-looking statements.

Item 9.01     Financial Statements and Exhibits

(d)           Exhibits

99.1 PowerPoint presentation at the Conference Call on January 14, 2011.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	SIMULATIONS PLUS, INC.
Dated: January 14, 2011	By: /s/ Momoko Beran
	Momoko Beran
	Chief Financial Officer

EX-99.1

Exhibit 99.1

Simulations Plus, Inc.

(NASDAQ:SLP)

First Quarter FY 2011

Conference Call and Webinar

January 14, 2011

With the exception of historical information, the matters discussed in this
presentation are forward looking statements that involve a number of risks
and uncertainties. The actual results of the Company could differ
significantly from those statements. Factors that could cause or contribute
to such differences include, but are not limited to: continuing demand for
the Company’s products, competitive factors, the Company’s ability to
finance future growth, the Company’s ability to produce and market new
products in a timely fashion, the Company’s ability to continue to attract
and retain skilled personnel, and the Company’s ability to sustain or
improve current levels of productivity. Further information on the
Company’s risk factors is contained in the Company’s quarterly and
annual reports and filed with the Securities and Exchange Commission.

Safe Harbor Statement

•1Q11 was another record 1st quarter:

–13th consecutive profitable quarter

–1Q11 sales up 15.4% to $2.81 MM from $2.44 MM in 1Q10.

–Net Income up 32.0% for the quarter over 1Q10

–Pharmaceutical segment sales up 18.2% over 1Q10

–Words+ subsidiary sales up 8.3% over 1QFY10

•Strong balance sheet:

–Cash $8.87 MM at 11/30/10, after using cash of $2.2 million for share repurchases ($1.198
million in Phase I plus $1.002 million in Phase II)

–Shareholders’ equity up 15.4% to $12.5 million from $10.8 million at 11/30/09. Note: Since
August 30, 2010, shareholders’ equity decreased 4.5% to $12.5 million (due to cash used
for share repurchases).

–No debt.

SLP 1Q11 Highlights
Three months ended 11/30/10

Consolidated Revenue

Revenue History

Pharmaceutical Growth

Gross Margin (consolidated)

75.6%

78.9%

78.8%

70.4%

73.8%

74.4%

80.0%

67.9%

75.0%

76.3%

77.6%

75.6%

73.6%

Income Before Taxes

Net Income

$243K

$565K

$764K

$165K

$312K

$368K

$569K

$163K

$430K

$641K

$740K

$345K

$567K

Consolidated Income Statement

($ millions)

	1Q11	1Q10
Pharmaceutical software and services revenue	2.050	1.735
Words+ revenue	0.761	0.702
Consolidated revenue	2.811	2.437
Gross profit	2.070	1.830
Gross profit margin	73.6%	75.1%
SG&A	1.062	1.004
R&D	0.208	0.261
Total operating expenses	1.270	1.265
Income before income taxes	0.825	0.661
Net income	0.567	0.430
Earnings per share (diluted)	0.034	0.026

Select Balance Sheet Items

($ millions)

	November 30, 2010	November 30, 2009
Cash and cash equivalents	$8.87	$7.97
Total current assets	11.775	10.750
Total assets	$14.063	$12.828
Total current liabilities	1.095	1.227
Total liabilities	1.581	2.017
Shareholders’ equity	12.482	10.812
Total liabilities and shareholders’ equity	14.063	12.828

Share Repurchase Program

•The board of directors approved a second share repurchase
program beginning February 2010 for one year (Phase II)

•The Phase II program authorizes repurchase of up to
1,000,000 shares through February 2011

•The purpose of the program is to use some of our excess cash
to increase shareholder value by reducing the number of
shares outstanding and increasing the per-share metrics (EPS,
sales/share, etc.)

•As of today, the company has repurchased approximately
816,000 shares at an average price of $2.6935 per share, so
an additional approximately 184,000 shares are authorized to
be repurchased. We intend to continue the repurchase;
however, the company does not announce when and if further
repurchases may be made, nor a price range for repurchases.

Aggressive Marketing and Sales Program

•Our development and consulting scientists
continue to be actively involved in scientific
meetings, with numerous poster and podium
presentations and staffing exhibit booths

•Fundamental industry shift continues

–Pharma increasingly utilizing simulation software and modeling
tools to increase productivity

–Software tools are always evolving, and as the technology
advances, new capabilities attract new users, such as the improved
and expanded structure-property models in ADMET Predictor 5.0;
the drug-drug interaction, ocular and nasal/pulmonary delivery
capabilities in GastroPlus 7.0; and the powerful de novo molecule
design capabilities in MedChem Studio, all of which were released
in the 4th quarter of FY10

–Collaborations/Consulting/Grants

–Marketing and sales emphasis on our consulting capabilities is
paying off - consulting, training, and collaboration revenues
increased from $773,000 in FY09 to $907,000 in FY10

–Funded longer-term collaborations completed in FY10 resulted in
lower revenue from $210K in 1QFY10 to $145K in 1QFY11.

•Simulations Plus continues to increase its technological advantage

Ongoing Enhancements

•Version 7.0 was released in August - a major upgrade

•Three new market-expanding capabilities plus numerous features:

•Drug-to-drug interaction

•Ocular drug delivery

•Nasal/pulmonary drug delivery

•Version 5.0 was released in August - major upgrade

•SBIR grant is funding major effort toward very rapid calculation of
proprietary quantum-level descriptors, which have been incorporated

•Prediction of sites of metabolism in final test - release expected Q2

•Version 1.0 was released in August - major upgrade and name change

•Major enhancements to graphical user interface in development version

•Significant speed improvements achieved in development version

•Exciting new developments are in beta test in-house - release expected Q2

•Stable product with fine-tuning of capabilities

•Growing customer base shows gradual acceptance of this unique
technology by formulation scientists

•FDA Office of Generic Drugs added more licenses last year

WAR EAGLE!Auburn University wins National Championship!

Q&A