8-K

                                  UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934



                                 July 20, 2006
                      (Date of the earliest event reported)


                             Simulations Plus, Inc.
                             ----------------------
             (Exact name of Registrant as specified in its charter)


          California                   001-32046                 95-4595609
          ----------                   ---------                 ----------
(State or other jurisdiction    (Commission File Number)      (I.R.S. Employer
        of incorporation)                                    Identification No.)

                42505 10th Street West, Lancaster, California 93534
                 -----------------------------------------------
                    (Address of principal executive offices)
                                   (Zip Code)

                                 (661) 723-7723
                                 --------------
               Registrant's telephone number, including area code



ITEM 8.01         OTHER EVENTS.

         On July 20, 2006, Simulations Plus, Inc. (AMEX: SLP) announced that its
Board of Directors approved a two-for-one split of the Company's common stock.
Trading will begin on a split-adjusted basis on August 14, 2006.



ITEM 9.01         EXHIBITS AND REPORTS ON FORM 8-K.

(a) Exhibits

99.1     Press release dated July 20, 2006



                                   Signatures

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                                SIMULATIONS PLUS, INC.



Dated: July 20, 2006                            By: /s/ Walter Woltosz
                                                   -----------------------
                                                   Walter S. Woltosz
                                                   Chief Executive Officer



                                 EXHIBITS INDEX
                                 --------------


      Exhibit Number                             Description
      --------------                             -----------

           99.1                      Press release, dated July 20, 2006

EX-99.1

EXHIBIT 99.1


SIMULATIONS PLUS
Integrating Science and Software

For Further Information:
SIMULATIONS PLUS, INC.
42505 10th Street West
Lancaster, CA 93534-7059

CONTACT:
Investor Relations
- ------------------
Ms. Renee Bouche
Simulations Plus, Inc.
661.723.7723
info@simulations-plus.com

For Immediate Release:
July 20, 2006

                    SIMULATIONS PLUS ANNOUNCES STOCK DIVIDEND

               BOARD OF DIRECTORS APPROVES TWO-FOR-ONE STOCK SPLIT

LANCASTER, CA JULY 20, 2006 - Simulations Plus, Inc. (AMEX: SLP), a leading
provider of simulation and modeling software for pharmaceutical discovery and
development, announced today that its Board of Directors has approved a
two-for-one split of the Company's common stock. The number of authorized shares
remains at 20 million. Each shareholder of record at the close of business on
Monday, July 31, 2006 will receive a stock dividend certificate for one
additional share for every outstanding share held on the record date, and
trading will begin on a split-adjusted basis on August 14, 2006. In accordance
with the terms of the Stock Option Plan of 1996, employees with stock options
will benefit from the split by receiving twice the number of shares at one-half
the exercise price for options granted prior to the record date.

Walt Woltosz, chairman and chief executive officer of Simulations Plus, said,
"In the meetings we've had with investors and potential investors as part of our
investor relations program over several years, the `thin float' has been an
ongoing issue. This dividend forward split will result in the public float
increasing from about 1.6 million shares to about 3.2 million shares. The board
of directors has decided that a stock dividend is appropriate at this time
because of our demonstrated sustained growth and our expectation that this will
continue."

ABOUT SIMULATIONS PLUS, INC.

Simulations Plus, Inc. is a premier developer of groundbreaking drug discovery
and development simulation software, which is licensed to and used in the
conduct of drug research by major pharmaceutical and biotechnology companies
worldwide. We have two other businesses that are based on our proprietary
technologies: a wholly owned subsidiary, Words+, Inc., which provides assistive
technologies to persons with disabilities; and an educational software series
for science students in middle and high schools known as FutureLab(TM). For more
information, visit our Web site at www.simulations-plus.com.


                                       ###