Cancer Diagnostic Solutions Jon Cohen, M.D. Senior Vice President and Chief Medical Officer the new QUEST

Safe Harbor Disclosure This presentation may contain forward-looking statements. Readers are cautioned not to place undue reliance on forward-looking statements, which speak only as of the date that they are made and which reflect management's current estimates, projections, expectations or beliefs and which involve risks and uncertainties that could cause actual results and outcomes to be materially different. Risks and uncertainties that may affect the future results of the company include, but are not limited to, adverse results from pending or future government investigations, lawsuits or private actions, the competitive environment, changes in government regulations, changing relationships with customers, payers, suppliers and strategic partners and other factors discussed in "Business," "Risk Factors," "Cautionary Factors that May Affect Future Results," "Legal Proceedings," "Management's Discussion and Analysis of Financial Condition and Results of Operations," and "Quantitative and Qualitative Disclosures About Market Risk" in the company's 2011 Annual Report on Form 10-K and "Management's Discussion and Analysis of Financial Condition and Results of Operations," "Quantitative and Qualitative Disclosures About Market Risk," and "Risk Factors" in the company's Quarterly Reports on Form 10-Q and other items throughout the Form 10-K and the company's 2012 Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. the new QUEST

Comprehensive Cancer Diagnostic Solutions AmeriPath o Largest US pathology provider with its 300+ board-certified MDs and PhDs o Medical director and exclusive pathology group for 100+ hospitals Dermpath Diagnostics o Largest dermatopathology provider in the world with its 100+ board-certified physicians o Trains 85%+ of all dermatology residents in the US Quest Diagnostics o Largest pap provider in the US o Leader in esoteric and molecular diagnostics testing capabilities o 350+ MDs and PhDs Molecular Cancer Diagnostics Predisposition Screening Diagnosis Prognosis Treatment Monitoring the new QUEST 3 Restore Growth 3

Select Cancer Diagnostics Test Menu Today Continuum of Patient Care Cancer Type Breast Colon Leukemia/ Lymphoma Lung Skin Prostate Predisposition Screening Diagnosis Prognosis Treatment Monitoring Right Diagnostics Right Treatment Better Outcomes the new QUEST 3 Restore Growth 4

Strategic Partnerships with Hospitals and Integrated Health Networks the new QUEST

Continued Price and Utilization Pressure will Drive Demand for our Expertise in a Range of Strategic Partnerships Level of Strategic Partnership Esoteric Testing Microbiology Outsourcing Lab Management & Outsourcing Outreach Acquisition Joint Venture 50% of US Hospitals Multiple Midsized and Large Hospitals Six Contracts Covering Over 13 Hospitals and 3,500+ beds Three In The Last 24 Months Alone Six Joint Ventures In Place 14+ Years ACOs Scope of Services the new QUEST 3 Restore Growth 6

The Boston Globe UMASS Hospital Sells Part of Lab Unit By Robert Weisman Globe Staff October 16, 2012 UMass Memorial Medical Center in Worcester. which has been restructuring operations to improve its finances, said Tuesday it has signed an agreement to sell the hospital's clinical outreach laboratory business to Quest Diagnostic for an undisclosed price. The medical center, part of UMass Memorial Health Care -- the largest health care system in central Massachusetts -- said the sale was the first step toward an alliance in which UMass Memorial could take a financial stake in a new venture that would operate a state-of-the-art lab in Massachusetts. the new QUEST 3 Restore Growth 7

Hospital Lab Management Provides Multiple Benefits Reduce Fixed Costs Increase Revenue Reduce Variable Costs Improve Cash Flow Equipment Costs Supply Costs Personnel Costs Hospital Total Lab Costs Quest Diagnostics Lab Outsourcing Value Created the new QUEST 3 Restore Growth 8

Partnering with Hospitals to Help Manage Accountable Care Organizations (ACOs) 1 Bend the Cost Curve 2 Deliver Insights on Physician Behaviors and Testing Patterns Consolidating Data & Delivering Insights 3 Assess Population and Manage Wellness 4 Drive Patient Engagement & Close Gaps in Care Deliver Testing Management Solutions to Help Control Cost 5 Data Aggregation and Connectivity Solutions Patient Focused Programs to Enable Effective Management of Care, etc. the new QUEST 3 Restore Growth 9

Hospital - Quest Diagnostics Partnership Lab Mgmt. Joint Venture Monetize Outreach Human Resources TB Testing Improving Lab Efficiency Consolidated send out in house processing Broad I.T. support, E-pre, EMR, lab hub ACO Support Private Label Personal Health Record Cancer Diagnostic Center of Excellence Microbiology outsourcing Molecular Testing in hospital MRSA CDIFF Hospital-Quest Collaboration the new QUEST 3 Restore Growth 10