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CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Per Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Product related:      
Product revenue $ 36,416us-gaap_SalesRevenueGoodsNet $ 39,657us-gaap_SalesRevenueGoodsNet $ 36,695us-gaap_SalesRevenueGoodsNet
Cost of product revenue 21,188us-gaap_CostOfGoodsSold 22,602us-gaap_CostOfGoodsSold 20,616us-gaap_CostOfGoodsSold
Gross profit on product revenue 15,228us-gaap_GrossProfit 17,055us-gaap_GrossProfit 16,079us-gaap_GrossProfit
Government grants and cooperative agreements revenue 0us-gaap_RevenueFromGrants 0us-gaap_RevenueFromGrants 91us-gaap_RevenueFromGrants
Operating expenses:      
Research and development 21,800us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost 15,187us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost 7,603us-gaap_ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost
Selling, general and administrative 37,729us-gaap_SellingGeneralAndAdministrativeExpense 29,965us-gaap_SellingGeneralAndAdministrativeExpense 25,665us-gaap_SellingGeneralAndAdministrativeExpense
Amortization of intangible assets 202us-gaap_AmortizationOfIntangibleAssets 202us-gaap_AmortizationOfIntangibleAssets 202us-gaap_AmortizationOfIntangibleAssets
Total operating expenses 59,731us-gaap_OperatingExpenses 45,354us-gaap_OperatingExpenses 33,470us-gaap_OperatingExpenses
Loss from operations (44,503)us-gaap_OperatingIncomeLoss (28,299)us-gaap_OperatingIncomeLoss (17,300)us-gaap_OperatingIncomeLoss
Non-operating income (expense), net:      
Gain (loss) from revaluation of warrant liability 7,708us-gaap_FairValueAdjustmentOfWarrants (15,099)us-gaap_FairValueAdjustmentOfWarrants 2,059us-gaap_FairValueAdjustmentOfWarrants
Foreign exchange (loss) gain (1,296)us-gaap_ForeignCurrencyTransactionGainLossBeforeTax 533us-gaap_ForeignCurrencyTransactionGainLossBeforeTax 86us-gaap_ForeignCurrencyTransactionGainLossBeforeTax
Interest expense (599)us-gaap_InterestExpense (332)us-gaap_InterestExpense (551)us-gaap_InterestExpense
Other income, net 130us-gaap_OtherNonoperatingIncomeExpense 78us-gaap_OtherNonoperatingIncomeExpense 31us-gaap_OtherNonoperatingIncomeExpense
Total non-operating income (expense), net 5,943us-gaap_NonoperatingIncomeExpense (14,820)us-gaap_NonoperatingIncomeExpense 1,625us-gaap_NonoperatingIncomeExpense
Loss before income taxes (38,560)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments (43,119)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments (15,675)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
Provision for income taxes 195us-gaap_IncomeTaxExpenseBenefit 218us-gaap_IncomeTaxExpenseBenefit 242us-gaap_IncomeTaxExpenseBenefit
Net loss $ (38,755)us-gaap_NetIncomeLoss $ (43,337)us-gaap_NetIncomeLoss $ (15,917)us-gaap_NetIncomeLoss
Net loss per share:      
Basic $ (0.52)us-gaap_EarningsPerShareBasic $ (0.64)us-gaap_EarningsPerShareBasic $ (0.29)us-gaap_EarningsPerShareBasic
Diluted $ (0.61)us-gaap_EarningsPerShareDiluted $ (0.64)us-gaap_EarningsPerShareDiluted $ (0.33)us-gaap_EarningsPerShareDiluted
Weighted average shares outstanding used for calculating net loss per share:      
Basic 74,767us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 67,569us-gaap_WeightedAverageNumberOfSharesOutstandingBasic 54,515us-gaap_WeightedAverageNumberOfSharesOutstandingBasic
Diluted 76,534us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 67,569us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding 55,061us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding