Significant Components of Deferred Tax Assets (Detail) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2013	Dec. 31, 2012
Deferred tax assets:
Net operating loss carryforwards	$ 142,500	$ 137,700
Research and development credit carryforwards	32,100	30,800
Capitalized inventory costs	800	900
Inventory reserve	100	700
Capitalized research and development	12,300	9,100
Capitalized intangible asset	100	100
Deferred compensation	4,900	4,800
Accrued liabilities	200	100
Depreciation	1,300	1,300
Acquisition costs	200	200
Deferred tenant allowance	100	200
Capital loss carryforwards	3,900	3,900
Total deferred tax assets	199,000	190,500
Valuation allowance	(199,000)	(190,500)
Net deferred tax assets
Deferred tax liabilities:
Amortization of goodwill	89	62
Total deferred tax liabilities	89	62
Trademarks
Deferred tax assets:
Capitalized intangible asset	400	400
Capitalized Revenue Sharing Rights
Deferred tax assets:
Capitalized intangible asset	$ 100	$ 300