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STOCK-BASED COMPENSATION AND STOCK PLANS (Tables)
6 Months Ended
Jun. 30, 2017
Compensation and Retirement Disclosure [Abstract]  
Schedule of stock-based compensation expense
  Three Months Ended
June 30,
  Six Months Ended
June 30,
 
  2017  2016  2017  2016 
Research and development $74  $109  $204  $299 
General and administrative  212   312   625   716 
Total stock-based compensation expense $286  $421  $829  $1,015 
Schedule of activity of options under stock plans
Stock Options   Number of
Shares
    Weighted
Average
Exercise Price
 
Outstanding as of December 31, 2016     8,715,048     $ 3.71  
Granted     2,537,500       1.19  
Exercised            
Cancelled     (479,105 )     4.96  
Outstanding as of June 30, 2017     10,773,443     $ 3.06  
                 
Exercisable as of June 30, 2017     6,484,316     $ 4.16  
 
Schedule of shares vested, expected to vest and exercisable
    Shares     Weighted-
Average
Exercise Price
    Weighted-
Average
Remaining
Contractual
Term (in years)
    Aggregate
Intrinsic
Value
 
Vested and unvested expected to vest at June 30, 2017     10,566,460     $ 3.06       6.2     $ 479  
Exercisable at June 30, 2017     6,484,316     $ 4.16       4.3     $ 37