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STOCK-BASED COMPENSATION AND STOCK PLANS (Tables)
6 Months Ended
Jun. 30, 2016
Compensation and Retirement Disclosure [Abstract]  
Schedule of stock-based compensation expense
   

Three Months Ended

June 30,

   

Six Months Ended

June 30,

 
    2016     2015     2016     2015  
Research and development   $ 109     $ 124     $ 299     $ 396  
General and administrative     312       298       716       844  
Total stock-based compensation expense   $ 421     $ 422     $ 1,015     $ 1,240  
Schedule of activity of options under stock plans
Stock Options  

Number of

Shares

   

Weighted Average

Exercise Price

 
Outstanding as of December 31, 2015     8,305,950     $ 4.24  
Granted     1,609,000       1.78  
Exercised     (97,498 )     1.16  
Cancelled     (628,254 )     5.31  
Outstanding as of June 30, 2016     9,189,198     $ 3.77  
                 
Exercisable as of June 30, 2016     6,103,542     $ 4.78  
Schedule of shares vested, expected to vest and exercisable
    Shares    

Weighted-Average

Exercise Price

   

Weighted-Average

Remaining

Contractual

Term (in years)

   

Aggregate

Intrinsic

Value

 
Vested and unvested expected to vest at June 30, 2016     9,020,805     $ 3.77       5.8     $ 979  
Exercisable at June 30, 2016     6,103,542     $ 4.78       4.2     $ 203  
Schedule of restricted stock activity
Restricted Stock   Number of Shares    

Weighted Average

Grant Date

Fair Value

 
Unvested as of December 31, 2015     58,635     $ 2.51  
Vested     (29,306 )     2.51  
Cancelled     (53 )     2.51  
Unvested as of June 30, 2016     29,276     $ 2.51