COLLABORATIONS AND ALLIANCES (Detail Textuals 3) (USD $)	3 Months Ended								12 Months Ended			0 Months Ended	1 Months Ended	3 Months Ended	12 Months Ended			1 Months Ended
	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2011	Sep. 30, 2011	Jun. 30, 2011	Mar. 31, 2011	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010	May 07, 2007 Kyowa Hakko Kirin Licensing Agreement	Apr. 27, 2007 Kyowa Hakko Kirin Licensing Agreement	Mar. 31, 2007 Kyowa Hakko Kirin Licensing Agreement	Dec. 31, 2012 Kyowa Hakko Kirin Licensing Agreement	Dec. 31, 2011 Kyowa Hakko Kirin Licensing Agreement	Dec. 31, 2010 Kyowa Hakko Kirin Licensing Agreement	Sep. 30, 2010 Kyowa Hakko Kirin Licensing Agreement Phase Two trial Kyowa Hakko Kirin	Aug. 31, 2011 Kyowa Hakko Kirin Licensing Agreement Phase Three Attention Trial Asia	Feb. 29, 2008 Kyowa Hakko Kirin Licensing Agreement Kyowa Hakko Kirin
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront payment received												$ 27,000,000		$ 3,000,000
Potential development and sales milestone payments for each product selected for clinical development													123,000,000
Cash upfront licensing payments - total to date													30,000,000
Milestone payment received																		5,000,000	10,000,000	3,000,000
Percentage of royalties expected to be received - lower range																				mid-teen percent
Percentage of royalties expected to be received - upper range																				low-twenty percent
Notice period for termination of contract															90 days
Research and development revenue	5,143,000	10,944,000	11,829,000	8,498,000	16,504,000	11,954,000	5,447,000	13,405,000	36,414,000	47,310,000	29,221,000				5,700,000	10,100,000	6,100,000
Deferred revenue															$ 19,000,000	$ 24,700,000