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Share capital (Details 2) - Equity Option [Member] - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Statement [Line Items]        
Stock-based compensation pertaining to general and administrative expenses $ 0 $ 91,408 $ 368,151 $ 1,486,374
Stock-based compensation pertaining to research and development expenses 32,369 83,038 140,482 395,762
Total $ 32,369 $ 174,446 $ 508,633 $ 1,882,136