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Share capital (Details 2) - USD ($)
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Share Capital Details 2Abstract    
Stock-based compensation pertaining to general and administrative $ 214,439 $ 338,717
Stock-based compensation pertaining to research and development 393,071 351,755
Total stock-based compensation expense recognized $ 607,510 $ 690,472