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Share capital (Tables)
3 Months Ended
Mar. 31, 2019
Disclosure of classes of share capital [abstract]  
Weighted average exercise price, and the weighted average remaining contractual life

          Options        
          outstanding     Weighted  
          Weighted     average  
          average     remaining  
          exercise     contractual  
    Number     Price     life (in years)  
Outstanding, December 31, 2018     5,740,000     $ 1.76       6.37  
Expired                    
Cancelled                  
Granted                    
Outstanding, March 31, 2019     5,740,000     $ 1.76       6.13  
Options exercisable     5,740,000     $ 1.76       6.13  

Stock and stock option-based compensation expense

    Three months  
    ended March 31,  
Employee expense   2019     2018  
Stock and stock option compensation granted in            
2015     677,434       1,006,805  
2018     13,038        
Total stock-based compensation expense recognized   $ 690,472     $ 1,006,805  

Stock-based compensation expense

    Three months  
    ended March 31,  
    2019     2018  
Stock-based compensation pertaining to general and administrative expenses   $ 338,717     $ 503,402  
Stock-based compensation pertaining to research and development expenses     351,755       503,403  
Total   $ 690,472     $ 1,006,805