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Share capital (Details 1) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Disclosure of terms and conditions of share-based payment arrangement [line items]        
Total stock-based compensation expense recognized $ 1,170,697 $ 2,305,873 $ 3,091,466 $ 5,188,221
Stock options granted in 2015 [member]        
Disclosure of terms and conditions of share-based payment arrangement [line items]        
Total stock-based compensation expense recognized 828,876 1,222,498 2,749,645 4,069,246
Stock options granted in 2016 and 2017 [member]        
Disclosure of terms and conditions of share-based payment arrangement [line items]        
Total stock-based compensation expense recognized 1,083,375 1,118,975
Stock options granted in 2018 [member]        
Disclosure of terms and conditions of share-based payment arrangement [line items]        
Total stock-based compensation expense recognized $ 341,821 $ 341,821