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Financial Instruments (Details)
€ in Millions, $ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
EUR (€)
Sep. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Derivatives, Fair Value [Line Items]              
Derivative, Notional Amount           $ 9,000 $ 11,600
Gain (loss) recorded in Accumulated other comprehensive loss $ (175) $ 117 $ (113) $ (98)      
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) 8 37 (26) 93      
Foreign Currency Cash Flow Hedge Loss to be Reclassified During Next 12 Months           3  
(Gain) Loss recognized in Other income, net $ (1) $ (4) $ (9) $ (33)      
Notes 2.150% Due 2030 [Member]              
Derivatives, Fair Value [Line Items]              
Long-term debt, euro-denominated | €         € 500    
Other Current Assets [Member]              
Derivatives, Fair Value [Line Items]              
Derivatives designated as hedging instruments, Asset Derivatives           91 197
Derivatives not designated as hedging instruments, Asset Derivatives           12 44
Accrued Liabilities [Member]              
Derivatives, Fair Value [Line Items]              
Derivatives designated as hedging instruments, Liability Derivatives           111 66
Derivatives not designated as hedging instruments, Liability Derivatives           $ 22 $ 32