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Financial Instruments (Details)
€ in Millions, $ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Jun. 30, 2021
EUR (€)
Jun. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Derivatives, Fair Value [Line Items]              
Derivative, Notional Amount           $ 9,300 $ 11,600
Gain (loss) recorded in Accumulated other comprehensive loss $ 108 $ 188 $ 62 $ (215)      
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) (20) 27 (34) 56      
Foreign Currency Cash Flow Hedge Gain to be Reclassified During Next 12 Months           53  
Gain recognized in Other income, net $ 0 $ 10 $ (8) $ (29)      
Notes 2.150% Due 2030 [Member]              
Derivatives, Fair Value [Line Items]              
Long-term debt, euro-denominated | €         € 500    
Other Current Assets [Member]              
Derivatives, Fair Value [Line Items]              
Derivatives designated as hedging instruments, Asset Derivatives           224 197
Derivatives not designated as hedging instruments, Asset Derivatives           23 44
Accrued Liabilities [Member]              
Derivatives, Fair Value [Line Items]              
Derivatives designated as hedging instruments, Liability Derivatives           70 66
Derivatives not designated as hedging instruments, Liability Derivatives           $ 25 $ 32