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Financial Instruments (Details)
€ in Millions, $ in Millions
3 Months Ended
Mar. 31, 2021
USD ($)
Mar. 31, 2020
USD ($)
Mar. 31, 2021
EUR (€)
Dec. 31, 2020
USD ($)
Derivatives, Fair Value [Line Items]        
Derivative, Notional Amount $ 11,100     $ 11,600
Gain (loss) recorded in Accumulated other comprehensive loss (46) $ (403)    
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) (14) 29    
Foreign Currency Cash Flow Hedge Loss to be Reclassified During Next 12 Months 22      
Gain recognized in Other income, net (8) $ (39)    
Notes 2.150% Due 2030 [Member]        
Derivatives, Fair Value [Line Items]        
Long-term debt, euro-denominated | €     € 500  
Other Current Assets [Member]        
Derivatives, Fair Value [Line Items]        
Derivatives designated as hedging instruments, Asset Derivatives 171     197
Derivatives not designated as hedging instruments, Asset Derivatives 22     44
Accrued Liabilities [Member]        
Derivatives, Fair Value [Line Items]        
Derivatives designated as hedging instruments, Liability Derivatives 105     66
Derivatives not designated as hedging instruments, Liability Derivatives $ 62     $ 32