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Financial Instruments (Details)
€ in Millions, $ in Millions
12 Months Ended
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Dec. 31, 2020
EUR (€)
Derivatives, Fair Value [Line Items]      
Derivative, Notional Amount $ 11,600 $ 13,000  
Gain (loss) recorded in Accumulated other comprehensive loss 181 (33)  
(Gain) loss reclassified from Accumulated other comprehensive loss into Product sales (effective portion) 82 51  
Long-term debt, euro-denominated | €     € 500
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months 23    
Foreign exchange contracts gain (loss) (76) 91  
Other Current Assets [Member]      
Derivatives, Fair Value [Line Items]      
Derivatives designated as hedging instruments - assets 197 23  
Derivatives not designated as hedging instruments - assets 44 23  
Accrued Liabilities [Member]      
Derivatives, Fair Value [Line Items]      
Derivatives designated as hedging instruments - liabilities 66 166  
Derivatives not designated as hedging instruments - liabilities $ 32 $ 116