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Financial Instruments (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Dec. 31, 2018
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives $ 35   $ 35   $ 22
Derivatives not designated as hedging instruments, Asset Derivatives 86   86   63
Derivatives designated as hedging instruments, Liability Derivatives 149   149   194
Derivatives not designated as hedging instruments, Liability Derivatives 82   82   92
Four Quarter Rolling Average of Notional Amount of Foreign Exchange Contracts Hedging Foreign Currency Transactions 18,200   $ 18,200   20,100
Description of Net Investment Hedge Activity     We have €4.95 billion of euro-denominated long-term debt and €750 million of euro-denominated commercial paper borrowings outstanding, which qualify as a net investment hedge against our investments in European businesses. As of June 30, 2019, the net investment hedge is deemed to be effective.    
Gain (loss) recorded in Accumulated other comprehensive loss 21 $ (245) $ 28 $ (200)  
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) 16 (1) $ 20 (28)  
Maximum Length of Time, Foreign Currency Cash Flow Hedge     4 years 22 days    
Gain recognized in Other income, net 18 $ 19 $ 36 $ 70  
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months (23)   (23)    
Other Current Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 16   16   10
Derivatives not designated as hedging instruments, Asset Derivatives 79   79   44
Other Noncurrent Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 19   19   12
Derivatives not designated as hedging instruments, Asset Derivatives 7   7   19
Accrued Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 59   59   83
Derivatives not designated as hedging instruments, Liability Derivatives 80   80   89
Other Long-term Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 90   90   111
Derivatives not designated as hedging instruments, Liability Derivatives $ 2   $ 2   $ 3