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Financial Instruments (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives $ 82   $ 82   $ 178
Derivatives not designated as hedging instruments, Asset Derivatives 68   68   75
Derivatives designated as hedging instruments, Liability Derivatives 60   60   18
Derivatives not designated as hedging instruments, Liability Derivatives 58   58   60
Four Quarter Rolling Average of Notional Amount of Foreign Exchange Contracts Hedging Foreign Currency Transactions 20,000   $ 20,000   19,100
Description of Net Investment Hedge Activity     We have approximately €4.95 billion of euro-denominated long-term debt and €750 million of euro-denominated commercial paper borrowings outstanding, which qualify as a net investment hedge against our investments in European businesses. As of September 30, 2018, the net investment hedge is deemed to be effective.    
Gain (loss) recorded in Accumulated other comprehensive loss 95 $ 310 $ (105) $ 440  
(Gain) loss reclassified from Accumulated other comprehensive loss into Product Sales (effective portion) 2 (24) $ (26) (14)  
Maximum Length of Time, Foreign Currency Cash Flow Hedge     4 years 25 days    
Gain recognized in Other income, net 16 $ 10 $ 86 $ 50  
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months 10   10    
Other Current Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 36   36   77
Derivatives not designated as hedging instruments, Asset Derivatives 48   48   70
Other Noncurrent Assets [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Asset Derivatives 46   46   101
Derivatives not designated as hedging instruments, Asset Derivatives 20   20   5
Accrued Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 25   25   10
Derivatives not designated as hedging instruments, Liability Derivatives 55   55   57
Other Long-term Liabilities [Member]          
Derivatives, Fair Value [Line Items]          
Derivatives designated as hedging instruments, Liability Derivatives 35   35   8
Derivatives not designated as hedging instruments, Liability Derivatives $ 3   $ 3   $ 3