Note 9 - Stock Option and Stock Plans (Tables)

12 Months Ended

Dec. 31, 2018

Notes Tables

Share-based Compensation, Stock Options, Activity [Table Text Block]

Stock Plans 1	Issue Date Range			Total Shares Authorized		Shares Issued		Shares Remaining
2008 Stock Incentive Plan	5/23/08	–	10/11/11		600,000		463,420		136,580
Amarillo Biosciences, Inc., 2018 Employee Stock Option Plan	9/26/18	–	9/26/28		6,000,000		950,000		5,050,000
Amarillo Biosciences, Inc., 2018 Officers, Directors, Employees, and Consultants Nonqualified Stock Option Plan	9/26/18	–	9/26/28		20,000,000		3,995,000		16,005,000

Employee Stock Option [Member]

Notes Tables

Share-based Compensation, Stock Options, Activity [Table Text Block]

Date	Number of Options Qualified	Number of Options Nonqualified	Weighted Average Exercise Price	Weighted Average Remaining Contractual Term (years)	Aggregate Intrinsic Value
Balance December 31, 2017	-	-	-	-	-
Granted September 26, 2018*	*950,000	3,995,000	$0.38	5
Exercised	-	-	-	-	-
Expired	-	-	-	-	-
Balance December 31, 2018*	*950,000	3,995,000	$0.38	5