-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 PVSnU59m2DMy4duCwjhgGONqR/+KBO0tg77w7PC13Ryfgm1CSUjycaMQGooXaJJL
 je4w1l10d6SHntiwGyL//Q==

<SEC-DOCUMENT>0001209191-10-021715.txt : 20100409
<SEC-HEADER>0001209191-10-021715.hdr.sgml : 20100409
<ACCEPTANCE-DATETIME>20100409124218
ACCESSION NUMBER:		0001209191-10-021715
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20100409
DATE AS OF CHANGE:		20100409
EFFECTIVENESS DATE:		20100409

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BioScrip, Inc.
		CENTRAL INDEX KEY:			0001014739
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				050489664
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-140341
		FILM NUMBER:		10741875

	BUSINESS ADDRESS:	
		STREET 1:		100 CLEARBROOK ROAD
		CITY:			ELMSFORD
		STATE:			NY
		ZIP:			10523
		BUSINESS PHONE:		914 460 1600

	MAIL ADDRESS:	
		STREET 1:		100 CLEARBROOK ROAD
		CITY:			ELMSFORD
		STATE:			NY
		ZIP:			10523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MIM CORP
		DATE OF NAME CHANGE:	19960516
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
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<edgarSubmission>

    <schemaVersion>X0603</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001014739</cik>
        <entityName>BioScrip, Inc.</entityName>
        <issuerAddress>
            <street1>100 Clearbrook Road</street1>
            <city>Elmsford</city>
            <stateOrCountry>NY</stateOrCountry>
            <zipCode>10523</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>914-460-1600</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>MIM Corporation</previousName>
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            <previousName>MIM CORP</previousName>
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        <entityType>Corporation</entityType>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName>Harris</middleName>
                <lastName>Friedman</lastName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName>Martin</middleName>
                <lastName>Smith</lastName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
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                <firstName>Stephen</firstName>
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                <street1>BioScrip, Inc.</street1>
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                <zipCode>10523</zipCode>
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            <relatedPersonName>
                <firstName>Russel</firstName>
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                <street1>BioScrip, Inc.</street1>
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            <relatedPersonName>
                <firstName>Dave</firstName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
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                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Scott</firstName>
                <middleName>William</middleName>
                <lastName>Friedman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Douglas</firstName>
                <middleName>Alan</middleName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
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            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Vito</firstName>
                <lastName>Ponzio, Jr.</lastName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
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                <zipCode>10523</zipCode>
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            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Barry</firstName>
                <middleName>Alan</middleName>
                <lastName>Posner</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stanley</firstName>
                <middleName>Guy</middleName>
                <lastName>Rosenbaum</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName>David</middleName>
                <lastName>Smith</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Charlotte</firstName>
                <middleName>Webb</middleName>
                <lastName>Collins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Louis</firstName>
                <middleName>Thomas</middleName>
                <lastName>DiFazio</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
                <street2>100 Clearbrook Road</street2>
                <city>Elmsford</city>
                <stateOrCountry>NY</stateOrCountry>
                <zipCode>10523</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Myron</firstName>
                <middleName>Zenon</middleName>
                <lastName>Holubiak</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
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                <zipCode>10523</zipCode>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName>Ray</middleName>
                <lastName>Hubers</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
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                <city>Elmsford</city>
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                <zipCode>10523</zipCode>
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            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName>Louis</middleName>
                <lastName>Robbins</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
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            <relatedPersonRelationshipList>
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            <relationshipClarification></relationshipClarification>
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        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Stuart</firstName>
                <middleName>Allen</middleName>
                <lastName>Samuels</lastName>
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            <relatedPersonAddress>
                <street1>BioScrip, Inc.</street1>
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            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
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            <relationshipClarification></relationshipClarification>
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    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Over $100,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-03-25</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>true</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>Indefinite</totalOfferingAmount>
            <totalAmountSold>109516262</totalAmountSold>
            <totalRemaining>Indefinite</totalRemaining>
            <clarificationOfResponse>The dollar amount of the securities sold is based on BioScrip's closing stock price of $8.35 on the date of first sale. Warrants exercisable for 3,400,945 shares of BioScrip common stock with a $10 exercise price and five year term were also issued.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>13</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
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            <clarificationOfResponse></clarificationOfResponse>
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        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>BioScrip, Inc.</issuerName>
                <signatureName>/s/ Barry A. Posner</signatureName>
                <nameOfSigner>Barry A. Posner</nameOfSigner>
                <signatureTitle>Executive Vice President, Secretary and General Counsel</signatureTitle>
                <signatureDate>2010-04-09</signatureDate>
            </signature>
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</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----