Consolidated Statements of Shareholders' Equity - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Accumulated Other Comprehensive Income (Loss) [Member]
Balance at Dec. 31, 2012	$ 30,504	$ 3,714	$ 209,158	$ (192,621)	$ 10,253
Balance (in shares) at Dec. 31, 2012		25,416
Net income (loss)	(42,925)	$ 0	0	(42,925)	0
Other comprehensive income (loss)	562	0	0	0	562
Subscription of warrants	(27)	0	(27)	0	0
Exercise of stock options or warrants	399	$ 8	391	0	0
Exercise of stock options or warrants (in shares)		50
Vesting of free shares	0	$ 24	(24)	0	0
Vesting of free shares (in shares)		147
Stock-based compensation expense	1,975	$ 0	1,975	0	0
Balance at Dec. 31, 2013	(9,512)	$ 3,746	211,473	(235,546)	10,815
Balance (in shares) at Dec. 31, 2013		25,613
Net income (loss)	(84,906)	$ 0	0	(84,906)	0
Other comprehensive income (loss)	(18,238)	0	0	0	(18,238)
Subscription of warrants	351	0	351	0	0
Exercise of stock options or warrants	6,025	$ 164	5,861	0	0
Exercise of stock options or warrants (in shares)		1,001
Vesting of free shares	0	$ 24	(24)	0	0
Vesting of free shares (in shares)		151
Stock-based compensation expense	2,894	$ 0	2,894	0	0
Public offering	115,232	$ 2,099	113,133	0	0
Public offering (in shares)		12,400
Shares granted to Recipharm AB	13,049	$ 155	12,894	0	0
Shares granted to Recipharm AB (in shares)		1,026
Balance at Dec. 31, 2014	24,895	$ 6,188	346,582	(320,452)	(7,423)
Balance (in shares) at Dec. 31, 2014		40,191
Net income (loss)	40,659	$ 0	0	40,659	0
Other comprehensive income (loss)	(15,234)	0	0	0	(15,234)
Subscription of warrants	601	0	601	0	0
Exercise of stock options or warrants	6,389	$ 123	6,266	0	0
Exercise of stock options or warrants (in shares)		899
Vesting of free shares	0	$ 20	(20)	0	0
Vesting of free shares (in shares)		151
Stock-based compensation expense	7,741	$ 0	7,741	0	0
Excess tax benefit from stock-based compensation	2,814	0	2,814	0	0
Balance at Dec. 31, 2015	$ 67,865	$ 6,331	$ 363,984	$ (279,793)	$ (22,657)
Balance (in shares) at Dec. 31, 2015		41,241