Property and Equipment (Details) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2012	Dec. 31, 2011
Total property and equipment	$ 65,478	$ 63,368
Less accumulated depreciation and amortization	(47,240)	(43,985)
Property and equipment, net	18,238	19,383
Land and Buildings [Member]
Total property and equipment	10,332	10,132
Laboratory Equipment [Member]
Total property and equipment	29,314	28,639
Office and Computer Equipment [Member]
Total property and equipment	5,135	4,641
Furniture, Fixtures and Fittings [Member]
Total property and equipment	20,697	19,956
Construction In Progress [Member]
Total property and equipment	$ 0	$ 0

The cumulative amount of depreciation, depletion and amortization (related to property, plant and equipment, but not including land) that has been recognized in the income statement.

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Gross amount of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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- Definition

Amount, net of accumulated depreciation, depletion and amortization, of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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