Property and Equipment (Tables)

12 Months Ended

Dec. 31, 2012

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment [Table Text Block]

The components of property and equipment were as follows:

	December 31,
(In thousands of U.S. dollars)	2011			2012
Land and buildings		10,132			10,332
Laboratory equipment		28,639			29,314
Office and computer equipment		4,641			5,135
Furniture, fixtures and fittings		19,956			20,697
Construction in progress		-			-
Total property and equipment		63,368			65,478
Less accumulated depreciation and amortization		(43,985	)		(47,240	)
Property and equipment, net		19,383			18,238