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Nature of business and summary of significant accounting policies (Tables)
12 Months Ended
Dec. 31, 2012
Accounting Policies [Abstract]  
Property, Plant and Equipment, Schedule of Significant Acquisitions and Disposals [Table Text Block]
Depreciation and amortization are computed using the straight-line method over the following estimated useful lives:

 

Land and buildings 20 years
Laboratory equipment 4 - 8 years
Office and computer equipment 3 years
Furniture, fixtures and fittings 5-10 years