Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows from operating activities:
Net loss	$ (137,464)	$ (77,329)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,493	815
Amortization of debt discount and debt issuance costs	6,052	1,248
Changes in deferred tax	26,025	(15,666)
Share-based compensation expense	7,013	8,872
Other adjustments	2,042	1,055
Net changes in assets and liabilities
Prepaid expenses and other current assets	30,815	(439)
Research and development tax credit receivable	30	2,796
Accounts payable & other current liabilities	(3,108)	4,232
Accrued expenses	227	895
Other assets and liabilities	(3,429)	(3,789)
Net cash used in operating activities	(70,304)	(77,310)
Cash flows from investing activities:
Purchases of property and equipment	(716)	(26)
Proceeds from the disposition of the Hospital Products	0	16,500
Proceeds from sales of marketable securities	83,828	102,224
Purchases of marketable securities	(3,414)	(61,769)
Net cash provided by investing activities	79,698	56,929
Cash flows from financing activities:
Payments for debt issuance costs	(4,804)	0
Payments for extinguishment of February 2023 Notes	(8,653)	0
Proceeds from stock option exercises and employee share purchase plan	2,682	263
Proceeds from issuance of shares off the at-the-market offering program	25,318	0
Net cash provided by financing activities	14,543	263
Effect of foreign currency exchange rate changes on cash and cash equivalents	(664)	(896)
Net change in cash and cash equivalents	23,273	(21,014)
Cash and cash equivalents at January 1	50,708	71,722
Cash and cash equivalents at December 31	73,981	50,708
Supplemental disclosures of cash flow information:
Income taxes (refunded) paid, net	(29,058)	76
Interest paid	$ 9,660	$ 6,469