Income Taxes - Deferred Taxes (Details) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Deferred tax assets:
Net operating loss carryforwards	$ 53,393	$ 34,399
Share-based compensation	4,684	4,108
Amortization	3,541	3,429
Orphan drug and R&D tax credit	4,964	4,964
Capitalized research costs	2,108	0
Other	1,521	662
Interest expense carryforward	1,216	1,591
Gross deferred tax assets	71,427	49,153
Deferred tax liabilities:
Prepaid expenses	(86)	(75)
Other	0	(925)
Gross deferred tax liabilities	(86)	(1,000)
Less: valuation allowances	(71,341)	(24,025)
Net deferred tax assets	$ 0	$ 24,128