Disposition of the Hospital Business - Unaudited Pro Forma Condensed Combined Statement of Income (Loss) (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Product sales	$ 22,334	$ 59,215	$ 103,269
Total operating expense	16,519	83,327	208,195
Operating income (loss)	5,815	(24,112)	(104,926)
Loss before income taxes	(5,082)	(38,582)	(113,197)
Cost of products	5,742	12,125	17,516
Research and development expenses	20,442	32,917	39,329
Selling, general and administrative expenses	32,405	30,183	100,359
Intangible asset amortization	406	816	6,619
Changes in fair value of contingent consideration	3,327	845	(22,731)
Other expense - changes in fair value of contingent consideration payable	435	378	$ (1,899)
Pro Forma
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Product sales	159	(58)
Total operating expense	8,127	67,235
Operating income (loss)	(7,968)	(67,293)
Loss before income taxes	(18,430)	(81,385)
As Reported
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Product sales	22,334	59,215
Total operating expense	16,519	83,327
Operating income (loss)	5,815	(24,112)
Loss before income taxes	(5,082)	(38,582)
Pro Forma Adjustments | Pro Forma
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Product sales	(22,175)	(59,273)
Total operating expense	(8,392)	(16,092)
Operating income (loss)	(13,783)	(43,181)
Loss before income taxes	(13,348)	(42,803)
Pro Forma Adjustments | Pro Forma | Disposal Group, Disposed of by Sale, Not Discontinued Operations
Error Corrections and Prior Period Adjustments Restatement [Line Items]
Cost of products	3,540	11,368
Research and development expenses	322	1,960
Selling, general and administrative expenses	797	1,102
Intangible asset amortization	406	816
Changes in fair value of contingent consideration	3,327	845
Other expense - changes in fair value of contingent consideration payable	$ 435	$ 378