UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 83,109	$ 9,774
Marketable securities	148,467	54,384
Accounts receivable	0	8,281
Inventories	0	3,570
Research and development tax credit receivable	3,058	2,107
Prepaid expenses and other current assets	47,054	4,264
Total current assets	281,688	82,380
Property and equipment, net	373	544
Operating lease right-of-use assets	2,866	3,612
Goodwill	16,836	18,491
Intangible assets, net	0	813
Research and development tax credit receivable	3,608	6,322
Other non-current assets	22,264	39,274
Total assets	327,635	151,436
Current liabilities:
Current portion of long-term contingent consideration payable	0	5,554
Current portion of operating lease liability	520	645
Accounts payable	2,660	6,100
Accrued expenses	16,398	19,810
Other current liabilities	3,431	3,875
Total current liabilities	23,009	35,984
Long-term debt	126,520	121,686
Long-term contingent consideration payable, less current portion	0	11,773
Long-term operating lease liability	1,968	2,319
Other non-current liabilities	4,938	8,873
Liabilities, Total	156,435	180,635
Shareholders’ equity (deficit):
Preferred shares, nominal value of $0.01 per share; 50,000 shares authorized; 488 issued and outstanding at September 30, 2020 and none issued and outstanding at December 31, 2019, respectively	5	0
Ordinary shares, nominal value of $0.01 per share; 500,000 shares authorized; 58,243 issued and outstanding at September 30, 2020 and 42,927 issued and 37,520 outstanding at December 31, 2019	582	429
Treasury shares, at cost, 0 and 5,407 shares held at September 30, 2020 and December 31, 2019, respectively	0	(49,998)
Additional paid-in capital	565,440	434,391
Accumulated deficit	(372,909)	(391,215)
Accumulated other comprehensive loss	(21,918)	(22,806)
Total shareholders’ equity (deficit)	171,200	(29,199)
Total liabilities and shareholders’ equity (deficit)	$ 327,635	$ 151,436