Equity Instruments and Share-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2019

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs

Compensation expense included in the Company’s consolidated statements of (loss) income for all share-based compensation arrangements was as follows for the periods ended December 31, 2019, 2018 and 2017, respectively:

Share-based Compensation Expense:	2019			2018		2017
Research and development	$	429		$	880	$	672
Selling, general and administrative	2,154			6,972		7,400
Restructuring costs	(2,064		)	—		—
Total share-based compensation expense	$	519		$	7,852	$	8,072

Schedule of Share Based Payment Award Stock Options and Warrant Grants Valuation Assumptions

The weighted-average assumptions under the Black-Scholes option-pricing model for stock option grants as of December 31, 2019, 2018 and 2017, are as follows:   

Stock Option Assumptions:	2019		2018		2017
Stock option grants:
Expected term (years)	6.25		6.25		6.25
Expected volatility	56.48	%	56.59	%	58.82	%
Risk-free interest rate	2.52	%	2.68	%	2.20	%
Expected dividend yield	—		—		—

Schedule of Share-based Compensation, Stock Options, Activity

A summary of the combined stock option activity and other data for the Company’s stock option plans for the year ended December 31, 2019 is as follows:   

Stock Option Activity and Other Data:	Number of Stock Options		Weighted Average Exercise Price per Share		Weighted Average Remaining Contractual Life	Aggregate Intrinsic Value
Stock options outstanding, January 1, 2019	4,601		$	11.39
Granted	2,631		2.24
Exercised	—		—
Forfeited	(1,333	)	7.37
Expired	(778	)	12.91
Stock options outstanding, December 31, 2019	5,121		$	7.51	7.43 years	$	12,119
Stock options exercisable, December 31, 2019	2,636		$	11.63	5.73 years	$	572

Schedule of Stockholders' Equity Note, Warrants or Rights

A summary of the combined warrant activity and other data for the year ended December 31, 2019 is as follows:   

Warrant Activity and Other Data:	Number of Warrants		Weighted Average Exercise Price per Share		Weighted Average Remaining Contractual Life	Aggregate Intrinsic Value
Warrants outstanding, January 1, 2019	596		$	17.72
Granted	—		—
Exercised	—		—
Forfeited	—		—
Expired	(305	)	21.67
Warrants outstanding, December 31, 2019	291		$	13.59	0.61 years	$	—
Warrants exercisable, December 31, 2019	291		$	13.59	0.61 years	$	—

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award

A summary of the Company’s restricted share awards as of December 31, 2019, and changes during the year then ended, is reflected in the table below. 

Restricted Share Activity and Other Data:	Number of Restricted Share Awards		Weighted Average Grant Date Fair Value
Non-vested restricted share awards outstanding, January 1, 2019	491		$	7.20
Granted	251		2.47
Vested	(153	)	7.50
Forfeited	(242	)	5.65
Non-vested restricted share awards outstanding, December 31, 2019	347		$	4.73