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Equity Instruments and Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2019
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs
Compensation expense included in the Company’s consolidated statements of (loss) income for all share-based compensation arrangements was as follows for the periods ended December 31, 2019, 2018 and 2017, respectively:
Share-based Compensation Expense:
 
2019
 
2018
 
2017
 
 
 
 
 
 
 
Research and development
 
$
429

 
$
880

 
$
672

Selling, general and administrative
 
2,154

 
6,972

 
7,400

Restructuring costs
 
(2,064
)
 

 

Total share-based compensation expense
 
$
519

 
$
7,852

 
$
8,072

Schedule of Share Based Payment Award Stock Options and Warrant Grants Valuation Assumptions
The weighted-average assumptions under the Black-Scholes option-pricing model for stock option grants as of December 31, 2019, 2018 and 2017, are as follows:   
Stock Option Assumptions:
 
2019
 
2018
 
2017
 
 
 
 
 
 
 
Stock option grants:
 
 

 
 

 
 

Expected term (years)
 
6.25

 
6.25

 
6.25

Expected volatility
 
56.48
%
 
56.59
%
 
58.82
%
Risk-free interest rate
 
2.52
%
 
2.68
%
 
2.20
%
Expected dividend yield
 

 

 

Schedule of Share-based Compensation, Stock Options, Activity
A summary of the combined stock option activity and other data for the Company’s stock option plans for the year ended December 31, 2019 is as follows:   
 Stock Option Activity and Other Data:
 
Number of Stock
Options
 
Weighted Average
Exercise Price per Share
 
Weighted Average
Remaining
Contractual Life
 
Aggregate
Intrinsic Value
 
 
 
 
 
 
 
 
 
Stock options outstanding, January 1, 2019
 
4,601

 
$
11.39

 
 
 
 

Granted
 
2,631

 
2.24

 
 
 
 

Exercised
 

 

 
 
 
 

Forfeited
 
(1,333
)
 
7.37

 
 
 
 

Expired
 
(778
)
 
12.91

 
 
 
 
Stock options outstanding, December 31, 2019
 
5,121

 
$
7.51

 
7.43 years
 
$
12,119

Stock options exercisable, December 31, 2019
 
2,636

 
$
11.63

 
5.73 years
 
$
572

Schedule of Stockholders' Equity Note, Warrants or Rights
A summary of the combined warrant activity and other data for the year ended December 31, 2019 is as follows:   
 Warrant Activity and Other Data:
 
Number of
Warrants
 
Weighted Average Exercise Price per Share
 
Weighted Average Remaining
Contractual Life
 
Aggregate Intrinsic
Value
 
 
 
 
 
 
 
 
 
Warrants outstanding, January 1, 2019
 
596

 
$
17.72

 
 
 
 

Granted
 

 

 
 
 
 

Exercised
 

 

 
 
 
 

Forfeited
 

 

 
 
 
 

Expired
 
(305
)
 
21.67

 
 
 
 
Warrants outstanding, December 31, 2019
 
291

 
$
13.59

 
0.61 years
 
$

Warrants exercisable, December 31, 2019
 
291

 
$
13.59

 
0.61 years
 
$

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award
A summary of the Company’s restricted share awards as of December 31, 2019, and changes during the year then ended, is reflected in the table below. 
Restricted Share Activity and Other Data:
 
Number of Restricted Share Awards
 
Weighted Average Grant Date
Fair Value
 
 
 
 
 
Non-vested restricted share awards outstanding, January 1, 2019
 
491

 
$
7.20

Granted
 
251

 
2.47

Vested
 
(153
)
 
7.50

Forfeited
 
(242
)
 
5.65

Non-vested restricted share awards outstanding, December 31, 2019
 
347

 
$
4.73