Consolidated Statements of (Loss) Income - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Revenues:
Total revenues	$ 59,215	$ 103,269	$ 173,245
Operating expenses:
Cost of products	12,125	17,516	16,301
Research and development expenses	32,917	39,329	33,418
Selling, general and administrative expenses	30,183	100,359	58,860
Intangible asset amortization	816	6,619	3,659
Changes in fair value of related party contingent consideration	845	(22,731)	(31,040)
Impairment of intangible asset	0	66,087	0
Restructuring costs	6,441	1,016	2,542
Total operating expenses	83,327	208,195	83,740
Operating (loss) income	(24,112)	(104,926)	89,505
Investment and other income, net	1,069	452	2,136
Interest expense	(12,483)	(10,622)	(1,052)
Loss on deconsolidation of subsidiary	(2,678)	0	0
Other (expense) income - changes in fair value of related party payable	(378)	1,899	2,071
(Loss) income before income taxes	(38,582)	(113,197)	92,660
Income tax (benefit) provision	(5,356)	(17,893)	24,389
Net (loss) income	$ (33,226)	$ (95,304)	$ 68,271
Earnings (loss) per share
Net income (loss) per share - basic (in usd per share)	$ (0.89)	$ (2.55)	$ 1.69
Net income (loss) per share - diluted (in usd per share)	$ (0.89)	$ (2.55)	$ 1.63
Weighted average number of shares outstanding
Weighted average number of shares outstanding - basic (in shares)	37,403	37,325	40,465
Weighted average number of shares outstanding - diluted (in shares)	37,403	37,325	41,765
Product sales
Revenues:
Total revenues	$ 59,215	$ 101,423	$ 172,841
License revenue
Revenues:
Total revenues	$ 0	$ 1,846	$ 404