Company Operations by Product, Customer and Geographic Area - Revenue by Product (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Segment Reporting Information [Line Items]
Total revenues	$ 59,215	$ 103,269	$ 173,245
Bloxiverz
Segment Reporting Information [Line Items]
Total revenues	7,479	20,850	45,596
Vazculep
Segment Reporting Information [Line Items]
Total revenues	33,152	42,916	38,187
Akovaz
Segment Reporting Information [Line Items]
Total revenues	18,642	33,759	80,617
Other
Segment Reporting Information [Line Items]
Total revenues	(58)	3,898	8,441
Product sales
Segment Reporting Information [Line Items]
Total revenues	59,215	101,423	172,841
License revenue
Segment Reporting Information [Line Items]
Total revenues	$ 0	$ 1,846	$ 404