Revenue by Product - Summary of Revenue (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019 USD ($)	Sep. 30, 2018 USD ($)	Sep. 30, 2019 USD ($) segment	Sep. 30, 2018 USD ($)
Segment Reporting [Abstract]
Number of operating segments (in segments) | segment			1
Segment Reporting Information [Line Items]
Total revenues	$ 14,229	$ 19,826	$ 48,220	$ 82,349
Bloxiverz
Segment Reporting Information [Line Items]
Total revenues	1,466	3,656	6,392	16,691
Vazculep
Segment Reporting Information [Line Items]
Total revenues	8,786	8,759	27,669	33,097
Akovaz
Segment Reporting Information [Line Items]
Total revenues	4,208	5,991	13,946	28,083
Other
Segment Reporting Information [Line Items]
Total revenues	(231)	1,420	213	4,232
Product sales
Segment Reporting Information [Line Items]
Total revenues	14,229	19,826	48,220	82,103
License revenue
Segment Reporting Information [Line Items]
Total revenues	$ 0	$ 0	$ 0	$ 246