Company Revenue by Product - Summary of Revenue (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2019 USD ($) segment	Mar. 31, 2018 USD ($)
Segment Reporting [Abstract]
Number of operating segments (in segments) | segment	1
Segment Reporting Information [Line Items]
Total revenues	$ 16,437	$ 33,293
Bloxiverz
Segment Reporting Information [Line Items]
Total revenues	2,568	7,491
Vazculep
Segment Reporting Information [Line Items]
Total revenues	9,473	12,961
Akovaz
Segment Reporting Information [Line Items]
Total revenues	3,792	10,217
Other
Segment Reporting Information [Line Items]
Total revenues	604	2,492
Product sales
Segment Reporting Information [Line Items]
Total revenues	16,437	33,161
License revenue
Segment Reporting Information [Line Items]
Total revenues	$ 0	$ 132