Other Assets and Liabilities - Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Other Liabilities Disclosure [Abstract]
Accrued compensation	$ 3,971	$ 3,157
Accrued social charges	1,009	1,204
Accrued restructuring (see Note 17)	879	1,000
Customer allowances	6,541	10,613
Accrued ELAA payment	0	20,000
Accrued contract research organization charges	1,000	156
Accrued contract manufacturing organization costs	2,028	2,327
Accrued contract sales organization and marketing costs	3,469	7,641
Other	2,798	4,828
Total	$ 21,695	$ 50,926