Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 9,325	$ 16,564
Marketable securities	90,590	77,511
Accounts receivable	11,330	14,785
Inventories, net	4,770	6,157
Prepaid expenses and other current assets	8,836	8,958
Total current assets	124,851	123,975
Property and equipment, net	1,911	3,001
Goodwill	18,491	18,491
Intangible assets, net	1,629	92,289
Research and development tax credit receivable	7,272	5,272
Other non-current assets	36,146	10,249
Total assets	190,300	253,277
Current liabilities:
Current portion of long-term debt	106	111
Current portion of long-term related party payable	9,439	25,007
Accounts payable	3,503	7,477
Deferred revenue	114	2,007
Accrued expenses	21,695	50,926
Income taxes	73	414
Other current liabilities	3,453	597
Total current liabilities	38,383	86,539
Long-term debt, less current portion	115,734	156
Long-term related party payable, less current portion	19,401	73,918
Other non-current liabilities	14,002	7,084
Total liabilities	187,520	167,697
Shareholders’ equity:
Preferred shares, nominal value of $0.01 per share; 50,000 shares authorized; none issued or outstanding at December 31, 2018 and December 31, 2017, respectively	0	0
Ordinary shares, nominal value of $0.01 per share; 500,000 shares authorized; 42,720 issued and 37,313 outstanding at December 31, 2018, and 41,463 issued and 39,346 outstanding at December 31, 2017	427	414
Treasury shares, at cost, 5,407 and 2,117 shares held at December 31, 2018 and December 31, 2017, respectively	(49,998)	(22,361)
Additional paid-in capital	433,756	393,478
Accumulated deficit	(357,989)	(262,685)
Accumulated other comprehensive loss	(23,416)	(23,266)
Total shareholders’ equity	2,780	85,580
Total liabilities and shareholders’ equity	$ 190,300	$ 253,277