Equity Instruments and Stock Based Compensation (Tables)

12 Months Ended

Dec. 31, 2018

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs

Compensation expense included in the Company’s consolidated statements of (loss) income for all stock-based compensation arrangements was as follows for the periods ended December 31: 

Stock-based Compensation Expense:	2018		2017		2016
Research and development	$	880	$	672	$	3,523
Selling, general and administrative	6,972		7,400		11,156
Total stock-based compensation expense	$	7,852	$	8,072	$	14,679

Schedule of Share Based Payment Award Stock Options and Warrant Grants Valuation Assumptions

The weighted-average assumptions under the Black-Scholes option-pricing model for stock option and warrant grants as of December 31, 2018, 2017 and 2016, are as follows:   

Stock Option and Warrant Assumptions:	2018		2017		2016
Stock option grants:
Expected term (years)	6.25		6.25		6.25
Expected volatility	56.59	%	58.82	%	58.39	%
Risk-free interest rate	2.68	%	2.20	%	2.04	%
Expected dividend yield	—		—		—
Warrant grants:
Expected term (years)	—		0		2.50
Expected volatility	—	%	—	%	60.57	%
Risk-free interest rate	—	%	—	%	0.82	%
Expected dividend yield	—		—		—

Schedule of Share-based Compensation, Stock Options, Activity

A summary of the combined stock option activity and other data for the Company’s stock option plans for the year ended December 31, 2018 is as follows:   

Stock Option Activity and Other Data:	Number of Stock Options		Weighted Average Exercise Price per Share		Weighted Average Remaining Contractual Life	Aggregate Intrinsic Value
Stock options outstanding, January 1, 2018	5,041		$	11.34
Granted	138		6.67
Exercised	(82	)	6.52
Forfeited	(428	)	10.04
Expired	(68	)	12.41
Stock options outstanding, December 31, 2018	4,601		$	11.39	7.25 years	$	—
Stock options exercisable, December 31, 2018	3,005		$	11.99	6.66 years	$	—

Schedule of Stockholders' Equity Note, Warrants or Rights

A summary of the combined warrant activity and other data for the year ended December 31, 2018 is as follows:   

Warrant Activity and Other Data:	Number of Warrants		Weighted Average Exercise Price per Share		Weighted Average Remaining Contractual Life	Aggregate Intrinsic Value
Warrants outstanding, January 1, 2018	894		$	16.77
Granted	—		—
Exercised	—		—
Forfeited	—		—
Expired	(298	)	14.87
Warrants outstanding, December 31, 2018	596		$	17.72	1.03 years	$	—
Warrants exercisable, December 31, 2018	596		$	17.72	1.03 years	$	—

Disclosure of Share-based Compensation Arrangements by Share-based Payment Award

A summary of the Company’s restricted share awards as of December 31, 2018, and changes during the year then ended, is reflected in the table below. 

Restricted Share Activity and Other Data:	Number of Restricted Share Awards		Weighted Average Grant Date Fair Value
Non-vested restricted share awards outstanding, January 1, 2018	819		$	11.51
Granted	279		5.87
Vested	(548	)	12.78
Forfeited	(59	)	8.95
Non-vested restricted share awards outstanding, December 31, 2018	491		$	7.20