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Property and Equipment, net
12 Months Ended
Dec. 31, 2018
Property, Plant and Equipment [Abstract]  
Property and Equipment, net
Property and Equipment, net
The principal categories of property and equipment, net at December 31, 2018 and 2017, respectively, are as follows: 
Property and Equipment, net:
 
2018
 
2017
 
 
 
 
 
Laboratory equipment
 
$
8,864

 
$
10,135

Software, office and computer equipment
 
2,487

 
3,115

Furniture, fixtures and fittings
 
3,715

 
4,779

Less - accumulated depreciation
 
(13,155
)
 
(15,028
)
Total
 
$
1,911

 
$
3,001

 
Depreciation expense for the years ended December 31, 2018, 2017 and 2016 was $811, $1,224 and $601, respectively.